Peter Tass's latest paper: All about... - Cure Parkinson's

Cure Parkinson's

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Peter Tass's latest paper

claudejgreengrass profile image
9 Replies

All about coordinate reset but nothing about the glove.

Synaptic reorganization of synchronized neuronal networks with synaptic weight and structural plasticity

journals.plos.org/ploscompb...

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claudejgreengrass profile image
claudejgreengrass
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9 Replies
Boscoejean profile image
Boscoejean

"Background: Abnormal neuronal synchrony is associated with several neurological disorders, including Parkinson's disease (PD), essential tremor, dystonia, and epilepsy. Coordinated reset (CR) stimulation was developed computationally to counteract abnormal neuronal synchrony."

(expanding the research to help with several neurological disorders perhaps)

CuriousMe12 profile image
CuriousMe12 in reply toBoscoejean

Is the cue1 based on a similar theory?youtu.be/OqMeiK3OIgI?featur...

Boscoejean profile image
Boscoejean in reply toCuriousMe12

maybe somewhat based on the description:

"How does the CUE1 work?

The CUE1 uses a quiet electric motor to produce vibrotactile stimulation. The vibrations are produced in a specialised pattern developed through extensive research and testing alongside people with Parkinson’s.

Through the pattern’s wave shape and frequency, the device delivers two scientifically-validated principles in a combination unique to this device; focused stimulation and cueing. The scientific literature, as well as our own user testing, demonstrates their efficacy."

charconeurotech.com/the-sci....

davidhmtk profile image
davidhmtk

They are looking to explain their device's effectiveness in a measurable model (unlike DBS, which works similarly, but without a provable theory as to why.

Boscoejean profile image
Boscoejean in reply todavidhmtk

one thing that I find perplexing is why the Cue1 seems to work well for some who try it but does not work at all for others

claudejgreengrass profile image
claudejgreengrass in reply toBoscoejean

Essential tremor is not Parkinson's but there are parallels. Beta blockers 'work' for perhaps 50% of ET patients. Same is true for Primidone and ET.

Boscoejean profile image
Boscoejean in reply toclaudejgreengrass

neurologist gave these to my husband in 2017 when he (the neurologist) could not decide if the symptoms were essential tremor or Parkinson's but the two ET medications made him dizzy and caused a lot of nausea and we were not impressed

claudejgreengrass profile image
claudejgreengrass in reply toBoscoejean

A large number of people on social media complain that Propranolol has similar effects. Personally I would still be on beta blockers if it was for the very low heart rate that they cause me. I took them for 25+ years without and side effects until last autumn. As they say in the automotive trade. Your Mileage May Very. YMMV

AMA

Boscoejean profile image
Boscoejean in reply toclaudejgreengrass

Since my husband has always had blood pressure that was fairly low I think that both primidone and propranolol may have caused the blood pressure to go too low so I think your ideas on this are reasonable

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