Tyrosine & Mucuna

[staceysack]

Has anyone taken these together instead of C/L for tremors? Any negative effects anyone has had with Tyrosine? I went through prior posts but could not find much on this. Thank you for any information you can provide.

Have a fabulous day!!!

[Hope-full1970]

What does the Tyrosine do for the Mucuna? Does it help cross the blood brain barrier? I have never heard of that combination.

[staceysack in reply to Hope-full1970]

Apparently it does. I had not heard of it either until someone posted in a natural facebook group. She said she's been taking it for 2 years instead of C/L. I know that for me C/L does not work for my tremors. I have to take mucuna which does work but I have to take C/L to get the mucuna past the BBB. She does say that she can only take it in the morning or else it keeps her up at night more than usual. Tyrosine does cross the BBB - that much I have confirmed.

[Hope-full1970 in reply to staceysack]

Really interesting!! I'm going to ask my DO about Monday. He's an excellent Dr. I'll let you know if I find out any good information.

[staceysack in reply to Hope-full1970]

Thank you so much - I really appreciate it!

[Hope-full1970 in reply to staceysack]

Hi Stacey,I talked with my Dr. today. He said he ìs not familiar with the Mucuna/Tyrosine combination. He said if I want to try it, start with the Mucuna ,wait a week and see how you react. Keep a journal of all of your symptoms getting better or worse. After about a week add Tyrosine and journal any improvements.

I think it's worth a try😊

[staceysack in reply to Hope-full1970]

Thank you - I do well with mucuna. I'm interested to see if I do even better with tyrosine. Thanks again!

[Pixelpixie in reply to Hope-full1970]

follow

[MarionP in reply to staceysack]

Did you clarify a critically blank pronoun when you said something: "I have to take mucuna which does work but I have to take C/L to get the mucuna past the BBB. She does say that she can only take IT in the morning or else it keeps her up at night more than usual." RIGHT THERE, IT MATTERS VERY MUCH WHICH YOU MEAN BY " IT, " DO YOU MEAN CL OR MUCUNA?

[terni in reply to MarionP]

I think IT, in this case, refers to Tyrosine

[pdpatient in reply to terni]

Is everyone aware that Mucuna Pruriens (MP) is in fact just another form of Levodopa?

parkinsonsecrets.com/blog/7...

jnnp.bmj.com/content/75/12/...

[PDFree in reply to pdpatient]

Mucuna is not “just another form of L-dopa”. It is a natural form, not an Rx and doesn’t cause the undesirable, often irreversible side effects from long term use that C/L can.

I have taken large doses of high quality organic mucuna for several years and it works the same for me as the C/L. I know it doesn’t work for everyone but it does for me. I’m intrigued about combining with tyrosine, I’m going to give that a try.

[staceysack in reply to PDFree]

I agree and I am going to try it too.

[Pippaloola in reply to PDFree]

Can I ask how much higuh quality mucuna you take and what is it called ?

[staceysack in reply to Pippaloola]

I take Z Natural Foods 1/2teaspon 4 times a day. znaturalfoods.com/products/...

[PDFree in reply to Pippaloola]

1 tbsp powder mixed with a couple ounces of water, 5-7 times/day. Biopure and Banyan, both have worked well for me.

[staceysack in reply to MarionP]

I meant tyrosine... sorry for any confusion.

[Ingenity56]

Diagnosed '02, never use pharma. I've been using straight Tyrosine, 500mg BID since '05. I then added raw Mucuna Pruriens (MP) 5 grams per day from '18-'21.

Never used any decarb to get it passed the BBB. In my experience, Raw MP, a dopamine precursor, contains 3-7% L-Dopa, comes with it's own metabolism prereqs and does not require a decarb.

Increased Tyrosine to 500mg QID, from '23, so far. so good.

This has been the gist of treatments since diagnosis. Also, I've periodically experimented with nootropic to support the above treatments.

[Meg024 in reply to Ingenity56]

That's interesting. What do you mean by 500 mg BID and QID?

[terni in reply to Ingenity56]

Please help if you can. My HWP has never taken pharma. He started MP (NutraVita 99%, 1/4 tsp 2x per day) in 2021 . He had to take the powder in water because he can't swallow pills. Yet for all the time, he never noticed any benefit from the MP... nothing.

Frustrated, I made H an appt last Nov with a neurologist and it's comin up in May. I know the neuro will only talk C/L.

But now I see this. You take MP with Tyrosine. I do not want H to take big pharma. If I could have him try your regimen, I'm wondering how I can get both into him without pills? If you know if this is possible, will you share your routine, please?

[MarionP in reply to terni]

It matters the brand of mucuna very greatly, because ever aspect from the seedlot, soil, harvest time, harvest date, weather, and then processing all the way through to the end pill matters. So if somebody is having a benefit you need to get as much through them as you can to help you track down brand, product, even the lot number, and tap into the same or duplicate as many of these particulars along the way as possible. And hope to God the particular source of plant stock has been the same one throughout and that it was processed the same way from plant through to pill.

[staceysack in reply to Ingenity56]

Thank you - I really appreciate the information.

[RBan in reply to Ingenity56]

What brand Mucuna do u use?

[staceysack in reply to RBan]

I take Z Natural Foods 1/2teaspon 4 times a day. znaturalfoods.com/products/...

[Pippaloola in reply to staceysack]

Thanks a lot for info...

[Ingenity56]

Prescription short hand; BID = Bis In Die, twice a day

QID = Quater In Die, four times a day

mg = milligrams

[Gallowglass]

following. Thanks!

[ottercat]

It would best if you could find a Naturopath who follows the Hinz protocol. A tailored program could be set up that meets your needs and bodily idiosyncrasies. Look at naturalpathhealthcenter.com

I've been well cared for on this protocol since 2016 by Dr. Oler. There are a number of amino acid supplements that support the mucuna/tyrosine protocol.

Best wishes!

[staceysack in reply to ottercat]

Thank you for the information. I will look into this for sure.

[gomelgo in reply to staceysack]

I explored this last year and it ends up costing close to $500 per month as I understood it.

[gomelgo in reply to staceysack]

I was going to follow Dr Oler's protocol, but it would have been something like 500 per month, maybe more. I can't afford to get well at that rate sadly.

[Esperanto in reply to ottercat]

The Hinz protocol seems to be unstoppable... Realize that "small pharma" can also take advantage of you just as well. By linking carbidopa with manipulated research to higher mortality rates, Hinz hoped to make the leap to "big pharma" at the time. It's unbelievable that this fraud still continues through his herbal business. Feel free to be exploited, but I advise you to first read more about his shady practices.

quackwatch.org/11ind/a-skep...

[staceysack in reply to Esperanto]

I do not plan to follow that protocol. Unfortunately, even some of the "natural" people just want your money. Very sad!

[beehive23]

Yes was on both for 3 yrs, didnt work for anything i could notice. hang tough

[gigiwillms]

I’ve taken high doses of mucuna and tyrosine (Heinz Protocol - very expensive) as well as small doses of mucuna since 2019. Mucuna in large doses acts just like C/L and will give you side effects of dyskinesia. Mine started after about 2 1/2 years. Every day my blood pressure raised due to the tyrosine. I also vomited every day on higher doses because the amount of powder irritated my throat and aggravated my silent reflux. It was a small price to pay for the almost nonexistent tremor. However, around Jan 2021, I noticed that the mucuna and tyrosine on time wasn’t lasting as long and I was having dyskinesia. I went to a higher concentration of mucuna (Nutravita) with a much smaller dose and added C/L. It took me awhile to find the right combination and dosing for me, but my on time is much improved. If you’re already taking a dopamine agonist, Do Not take tyrosine! It could cause your blood pressure to raise dramatically.

[Estaheal]

I was taking 4- 100/25 C/L since 2021. In 2023 I started to supplement with 1 capsule of 20% Mucuna 2 x a day which helped with some side effects of C/L.

Since February I have been reducing the C/L and slightly increasing the Mucuna. Am now taking 3 half doses of 100/25 L/C (i.e. 50/12.5) with 4 Mucuna caps throughout the day. Plan to continue to reduce L/C and hopefully, eventually also the Mucuna. I am taking 1/4 cap Tyrosine 2 x a day as well as 1/8th tsp of Taurine and other amino acids and supplements. So far it is working very well.

The brand of Mucuna I use is from an extract (Zazzee 20% L-dopa). As an "extract" less desirable compounds such as anti nutrients and enzyme inhibitors have likely been removed.

My understanding is that Tyrosine is a precursor to dopamine, it helps to create dopamine and reduces the enzyme that breaks down dopamine so the dopamine circulates longer.

I have been consulting with a friend whose life study has been using food (and supplements) as medicine. One of his sayings, "Drugs can never act like vitamins, but vitamins can be toxic like a drug if you take too much." If you can find a really good naturopath or similar to work with might be helpful.

[staceysack]

Thank you all for the information. This has really helped me a lot. I appreciate all of you so much!!!! It's great to have a "team" to talk to since I am relatively new to all of this. Thanks again

[DIY4PD-GBA]

"Tyrosine should not be taken at the same time as levodopa, a medication used to treat Parkinson's disease. Levodopa may interfere with the absorption of tyrosine."

mountsinai.org/health-libra...

I have to wonder if tyrosine is likely similarly contraindicated with mucuna puriens?

[staceysack in reply to DIY4PD-GBA]

Thank you for that. I will have to look in to it more. Luckily I haven't purchased any yet.

[CapSage88008]

I have been taking Tyrosine + Mucuna for a few years. Note: I was told personally by Dr. Datis Kharrazian that the correct form of Tyrosine is: N-ACETYL L-TYROSINE, so that is the form I take.

[staceysack in reply to CapSage88008]

Thank you for that information. I appreciate it!