How long does one xadago last?

[Anteaters]

WHAT Ate the sid

[johntPM]

Xadago is safinamide.

[1] "elimination half-life of 20 to 30 hours. About 1.5% of safinamide is found excreted in the feces. Safinamide exhibits linear pharmacokinetics after oral administration of 50 mg to 300 mg (three times the maximum recommended daily dose) with a steady state reached within five to six days."

[2] "safinamide 100 mg corresponds to 125 mg of Levodopa, whereas safinamide 50 mg and rasagiline 1 mg equally correspond to 100 mg of Levodopa"

References

[1] "Xadago (Safinamide): A Monoamine Oxidase B Inhibitor for the Adjunct Treatment of Motor Symptoms in Parkinson’s Disease"

Martin Paspe Cruz,

ncbi.nlm.nih.gov/pmc/articl...

[2] "Levodopa Equivalent Dose of Safinamide: A Multicenter, Longitudinal, Case–Control Study"

Roberto Cilia

ncbi.nlm.nih.gov/pmc/articl...