Cell in a box

[st8farm]

Can anyone enlighten the group as to the "cell in a box" technology and its potential importance to Parkinsons treatment?

[Boscoejean]

sigmaaldrich.com/US/en/tech...

Cell-in-a-Box® Live Cell Encapsulation Nanotechnology

"WHAT IS CELL-IN-A-BOX® TECHNOLOGY?

The Cell-in-a-Box® technology from Austrianova enables one to encapsulate cells in a protective, semipermeable, cellulose based 2 mm bead. Small pores in the beads allow for nutrient and waste product exchange, but retain the cells within the beads. The beads are durable, do not elicit an immune response from the host and can withstand up to 6 months in an in vivo implant. These characteristics allow embedded cells to grow for longer periods than in traditional 2D cell culture."

link.springer.com/reference....

"Cell encapsulation is a technique whereby living cells are entrapped into a selectively permeable polymeric materials (membranes/beads) making them a potential tool for the treatment of various human illnesses such as Parkinson's disease, hemophilia, lysosomal storage disease (LSD), cancer and diabetes. The encapsulated cells become immune, i.e., the immune system of the host could not recognize them; therefore, it does not develop any potential immune response against encapsulated cells."

[Boscoejean]

sciencedirect.com/topics/bi...

pubmed.ncbi.nlm.nih.gov/148....