The 10 pesticides identified as directly toxic to these neurons included: four insecticides (dicofol, endosulfan, naled, propargite), three herbicides (diquat, endothall, trifluralin), and three fungicides (copper sulfate [basic and pentahydrate] and folpet). Most of the pesticides are still in use today in the United States.
Aside from their toxicity in dopaminergic neurons, there is little that unifies these pesticides. They have a range of use types, are structurally distinct, and do not share a prior toxicity .
I would add that some are considered valid for organic.
Structurally distinct is not enough of a review, the function is what matters and the function is that these are all extremely powerful formulations of redox and electron donors that are reactive enough, forcefully binding enough, to resist degradation and to seriously damage cell walls, damage dna trigger apoptosis or cancer. They're strong enough, in quantity, to trigger numerous mechanisms that starts cell death because they're bonding is so powerful and reactive.... Multiple chlorines, multiple flourines. They're like putting a rare earth magnet up against your cell phone, or like bleach to your skin. (Consider for example paraquat, which was not in the list of 10 but is definitely a PD offender.) Whether organic or not is really a distractor not a useful distinction, function is the key, many things in toxic quantity or chronic exposure are organic, it's what they do to the biochemistry that matters.
How do you go about signing up for studies being conducted for Angiogenesis as a potential cure for Parkinson's? Is it safe to participate? Do you usually have to travel to one particular place or are they set up in many places? Thanks for your help.
"Although it is an important and essential element in phytosanitary defence, for several years an information work has been underway on the negative and toxic effects of this element, which result in the reduction of the quantity of Copper usable during the vegetative cycle of agricultural crops by the European Union.
Professional Agriculture is very dependent on fungicidal Copper, so the employment reduction work is a slow procedure well evaluated and tested.
The European Union has put in place a number of projects aimed at finding ways to reduce the use of this chemical without causing major damage to crops."
Dicofol: 5 chlorines, basically is DDT. Endosulfan: 6 chlorines. Naled: 2 chlorines, banned by the EU for plant protection use. Also so far all of these have benzene. Problem is that we do need them for modern food production and protection. Diquat: lots of benzenes, but it breaks down in moisture so it's basically exposure to farm workers. Folpet: 3 chlorines.
So: Redoxes, multiple-chlorines/flourines and benzenes often in combinations. Don't tell me they have nothing in common.
What happens when you combine organophosphate with organochlorine? It's called Cyclo-Sarin a deadly nerve agent used in warfare. No one is looking at the use of combined agricultural chemicals. What happens when ammonium sulfate and industrial grade surfactants are added to the mix? 7/16/14 is my poisoning date with this chemical mixture.
Guesses anyone? Death, and if you survive you get Gulf War Syndrome→ALS and other NDDs
If you're lucky you survive the poisoning. At least initially. My neighbors cattle didn't. I've seen poisoning up close and personal.
I get the feeling that this regulatory malfeasance is intentional to thin the human herd. Don't they know they're part of said herd?
There's a new disease in town, it's called chronic interstitial nephritis of agricultural communities. Yep, that's me too, my right kidney will soon be removed and I'm not eligible for a transplant when the left one fails because of my ALS diagnosis. It's the quiet part Mayo Clinic won't say out loud. My youngest son's kidneys are crashing, I am incensed.
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