PB was also reported to protect against neurodegeneration in models of α-synuclein toxicity and Parkinson’s disease (Sturm et al., 2016; Ono et al., 2009).
TUDCA reduced amyloid deposition and improved cognition in APP/PS1 mice (Nunes et al., 2012). It also improved pathology and behavior in mouse models of Parkinson’s disease, HD, and ALS (reviewed by Ackerman and Gerhard, 2016).
My functional doctor has me taking tudca and sited the ALS study. However, it is not a script, it is a supplement. I am taking the BODYBIO brand, 2 capsules, 2x/day @ 500mg each, so 4 caps daily.
I have not noticed any benefit per se, but it’s hard to know what symptoms, or lack there of attributed to which supplements.
My functional doctor says that he’s read the number of studies saying that it’s great for neurological diseases like ALS and Parkinson’s and encouraged me to double my dose so that it was the same dosage as the studies.
I just dbled so we’ll see. What I am, hoping for, is just slower progression, right? I was diagnosed in October 2014 and I think I’m doing pretty well and unless you really knew me personally you wouldn’t know I had Parkinson’s if you saw me at the store or on the street.
I took a short break from supplements last year, and when I started my supplements back up, I accidentally only took this Tudca once a day instead of twice a day, so I was not getting the full dose that I originally was prescribed. So that’s why the doctor encouraged me to double my dose back to what it was supposed to be.
Yes, I apologize- I just now had a chance to sit and read it. Thank you so much for your update. I’m actually taking taking care of my father who was diagnosed two years ago (but has probably had P for about 4 years) and just read a positive article on TUDCA. So, I was curious what your experience had been. He’s on some traditional medications, but I’m a big believer in functional medicine and am always on the lookout for new things to try.
It sounds like you have a great doctor who has you on an effective protocol. That’s wonderful! I hope your new dose continues to keep everything in check (and, hopefully, even improve some things for you)!
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