Adaptive DBS is available ...

[MikeCosta]

Adaptive DBS is now approved in the EU and US. I was enrolled in the ADAPT-PD study. Please let me know if you have any questions

Here's a short overview that I captured from Gemini AI:

Based on the information available, the ADAPT-PD study has yielded positive outcomes, leading to significant advancements in Parkinson's Disease treatment. Here's a summary:  

FDA (& CE) Approval:

The ADAPT-PD trial provided crucial data that supported the FDA's approval of Medtronic's adaptive Deep Brain Stimulation (aDBS) system. This signifies that the study demonstrated the safety and effectiveness of aDBS.  

Improved Programming and Precision:

The study highlighted significant improvements in DBS programming speed and precision. The integration of technologies like the BrainSense™ Electrode Identifier (EI) has enabled clinicians to optimize DBS settings more efficiently.  

Personalized Therapy:

A key outcome is the validation of aDBS's ability to provide personalized therapy. By adapting stimulation in real-time based on individual brain activity, aDBS offers a more dynamic and responsive treatment approach.  

Enhanced Symptom Control:

The trial indicated that aDBS has the potential to improve symptom control for individuals with Parkinson's Disease, particularly those experiencing motor fluctuations and side effects from traditional DBS.  

Data on Brain Signals:

The study has given valuable data relating to local field potential signals within the brain of Parkinson's patients. This data will help to further improve the algorithms used within aDBS systems.  

In essence, the ADAPT-PD study has played a pivotal role in advancing DBS technology, paving the way for more effective and personalized treatment options for people with Parkinson's Disease.  

[cgreg]

Hello Mike. I have been referred by my MDS to a DBS team member whom I will meet next week. The adaptive DBS will be available over here in June according to the Medtronics rep. Were you able to experience both the standard DBS as well as the adaptive? How do they compare in terms of symptom relief?

[MikeCosta in reply to cgreg]

Hi  cgreg . Yes. I had standard cDBS for ~3 months before my neurologist unlocked aDBS. Both modes worked well, especially with my refractory tremor. Somewhat with dystonia & rigidity. Neutral to slightly worse with speech. With cDBS, I had to carry around the patient controller and increase or decrease the stim level to allevate tremor or dyskinesia periodically. In aDBS mode, I don't need to manually make the adjustments. With the "single-threshold" type, I experience 2-3 seconds of tremor before it senses and adjusts. I rarely experience dyskinesia. I tried "dual-threshold" earlier and found that it took too long to adjust. Please let me know if you have any other questions.

[cgreg in reply to MikeCosta]

Thank you so much, Mike. I will certainly have more questions in the coming days.

[MikeCosta in reply to cgreg]

My pleasure. Here is a video of a talk by Helen Bronte-Stewart - the lead ADAPT-PD study investigator. It's quite detailed: youtube.com/watch?v=TzM3yEe...(Not working as expected?)

[popo1]

congrats on your progress