What suppliments and dosages would you recommend? I've been trying to put together a list for parkinson's.

[Kraz]

supplimentsvitamin E - 1000 mg/day

Vitamin C - 2000 mg/ day, 1000 mg/morning and night

Vitamin K2 - 100 to 300 mg/day

Vitamin K1 - None

Vitamin Omega 3 - 10,000 mg (that'd how much it takes to get enough in the brain)

Alpha Lipolic Acid

Vitamin A

Vitamin D3 - 2000 iu/ day

Vitamin B1 - individual dependent

Vitamin B12 -> 1,000 mcg

Vitamin B2

Vitamin B6

Vitamin B3 - None

beta carotene - 25,000 iu/day

Potassium - 400 mg/day

Magnesium - 500 mg/ day

CoQ10

Target Deficiencies

glutathione -> antioxidant in the brain

Creatinine-> creates glutothione

ashwagandha -> increases testosterone, decreases cortisol

pine pollen -> may increase testosterone

melatonin -> helped microglia function and increased sleep quality

nicotine patch -> stimulant, neuroprotective

caffeine -> stimulant, neuroprotective

tudca -> stomach bile salts

Astaxanthin -> helps exercise and oxygenated tissues

black sesame seeds -> antioxidant

resveratrol -> antioxidant, lengthens telemerase

quecetin -> antioxidant

olives -> antioxidant

Insoluble fiber -> Butyrate

Milk thistle -> 300 mg

Possibly GABA and liver sausage because it may help devolve iron in the brain.

[crewmanwhite]

I have included a list of important nutritional supplements and doses in my book "Rethinking Parkinson's Disease" (rethinkingparkinsons.com/).

I have tried to avoid overloading our systems with too many supplements and included the critical ones, with research and how to take.

Some of the supplements you have listed are not needed and/or not effective.

[ElliotGreen]

Regarding Vitamin B6: Please Heed park_bear's advice.

"If you are taking high doses of vitamin B6, do not take it as pyridoxine, which is frequently what you get in multivitamins. Take pyridoxal-5-phosphate instead. It is readily available as a supplement."

From "The Cause Of Vitamin B-6 Toxicity"

healthunlocked.com/cure-par...

[jackritchie47]

Here's what I take...

Morning: Nature's Way (NW) Alive! Men's 50 Plus Ultra Potency Complete MVI

Pure Encapsulations SR Co-Q10 + PQQ (100 + 20)

Terry Naturally (TN) Clinical OPC (French Grape Seed Extract) 400mg

TN Curamed Brain (Curcumin + Rosemary + Sage) 2 capsules

Pure Encapsulations Ginkgo 160mg

Orthomolecular Products (OMP) Methyl B12 5,000mcg

TN Tri-Iodine 12.5mg

Pure Encapsulations Reduced Glutathione 100mg

Allergy Research Corp.(ARC) Lactobacillus (L.Plantarum, et.al.) 2 capsules on

empty stomach up to twice a day.

Afternoon: TN Healthy Feet and Nerves 2 capsules

Evening: TN Curamed 750mg (Curcumin)

TN Clinical OPC 400mg (French Grape Seed Extract)

Source Naturals Magtein (Magnesium Threonate) 2 capsules

Pure Encapsulations Reduced Glutathione 100mg

Pure Encapsulations SR Co-Q 10 + PQQ

OMP Orthomega Select DHA (DHA 500mg + EPA 130mg)

PRN (as needed): During flu/Covid season OMP Orthomune 2 caps morning

For Sleep: NW Sleep Tonight - 1 before bedtime

TN Melatonin EP 120 1 one hour before bedtime

Notes: Vitamins and minerals have antioxidant properties and support immune system.

Curamed is Curcumin which is anti-cancer, anti-inflammatory, anti-oxidant

and promotes Neurogenesis (Do not use turmuric as only 2 to 5% of turmeric is

curcumin).

Glutathione has anti-oxidant properties, anti-aging, detoxifies, supports immune

system and may help Parkinson's symptoms.

Fish Oil provides fatty acids DHA/EPA which help brain function and memory;

neuroprotective; anti-inflammatory and anti-depressant effects.

Grape Seed Extract has anti-cancer, immune system support effects.

Iodine is used for immune system, detoxification and energy.

CoQ 10 protects brain cells from oxidative damage and helps with cellular energy.

Magnesium Threonate is the only form that gets magnesium in the brain &

protected against motor deficits and dopamine neuron loss in mouse models.

(for constipation use Magnesium Citrate 150mg at bedtime)

Rosemary and Sage help focus and mental clarity; 30% reduction of amyloid

plaque.

Ginkgo is an anti-inflammatory, anti-oxidant and helps blood flow (circulation).

Gluten-free diet - Gluten is inflammatory and degrades Blood Brain Barrier.

Always check with your Doctor first, before starting anything and ask your Pharmacist to check for interactions. Doses can vary depending upon age, weight, kidney/liver function, etc. I am not taking prescription meds, I am fighting PD with a gluten-free diet, exercise, prayer and these supplements. I think there are other supplements worth researching as well as red light therapy, etc. This list might be overwhelming but my neurologist is aware and I am a pharmacist, for what it's worth.

[evenshoshan in reply to jackritchie47]

Hello and thank you for such a detailed list. As for your personal PD journey, what are the top five (5) supplements of the list that you feel and observe are the most effective?

[jackritchie47 in reply to evenshoshan]

Hello, 1. I would look for a good multiple vitamin/mineral supplement derived from whole foods and not synthetic. 2, Curcumin at least twice a day because promotes neurogenesis and is a great anti-inflammatory. 3. Glutathione twice a day for the reasons I listed. 4. CoQ10 twice a day 5. A quality Fish Oil capsule (DHA/EPA) daily. Besides the supplements, high intensity exercise (aerobics, biking, Rock Steady boxing, lifting some weight, etc.) for 30 to 60 minutes at least 3 times a week and gluten-free diet are hugely important no matter what stage of PD.

[evenshoshan in reply to jackritchie47]

Thank you for your prompt response, much appreciated, I will put it to practice.

[Thal]

greenmedinfo.com/disease/pa...

[Farooqji]

healthunlocked.com/cure-par...

[Alock2020]

It's an interesting list, and I've seen many of these vitamins and supplements recommended elsewhere on Healthunlocked. What I'm wondering is which of these has scientific studies, or at least many, many anecdotal recommendations to indicate effectiveness, partly because it's rather difficult to take 30 or more pills/day.

Also, I've come to believe that taking too many medications/vitamins/supplements can lead to drug interactions. Most doctors and pharmacists can research drug interactions on combinations of 3 or 4 substances at most. They can't tell you whether there will be interactions with more than that, and if you're taking a large number of pills, especially in significantly higher doses than normal, you may be doing some harm to yourself as a result.

[bradykin in reply to Alock2020]

Bingo!

[LAJ12345]

Hardys daily essential nutrients with added vitamers plus Restore gold covers many of those on your list in just 2 products. My husband takes these 2 at 12 Hardys and 16 restore gold per day.

Here is his full list

Supplement list.