NEWS! Scientists develop nanoparticles that can cross the blood-brain barrier

[PDWarrior1900]

This is treatment for 'brain cancer' but their research can be applied to PD, at some point, I believe.

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"The researchers pioneered a technique called layer-by-layer assembly, which they can use to create surface-functionalized nanoparticles that carry drugs in their core. The particles that the researchers developed for this study are coated with a peptide called AP2, which has been shown in previous work to help nanoparticles get through the blood brain barrier."

"The researchers then filled the particles with cisplatin, a commonly used chemotherapy drug. When these particles were coated with the targeting peptide, they were able to effectively kill glioblastoma tumour cells in the tissue model."

"The researchers then tried delivering the nanoparticles to mice, using a specialized surgical microscope to track the nanoparticles moving through the brain. They found that the particles’ ability to cross the blood-brain barrier was very similar to what they had seen in their human tissue model."

drugtargetreview.com/news/1...

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