Promoting Sirtuins is the target, NAD+ is the fuel

[Gcf51]

Known as the “guardians of genomes,” sirtuins are genes that protect organisms, from plants to mammals, against deterioration and diseases. When the genes sense the body is under physical stress, such as exercising or hunger, it sends out troops to defend the body. Sirtuins sustain genome integrity, promote DNA repair and have shown anti-aging related properties in model animals like increasing lifespan.

NAD+ is the fuel that drives the genes to work. But like a car cannot drive without its fuel, sirtuins require NAD+. Results from studies show that raising NAD+ level in the body activates sirtuins and increases lifespan in yeast, worms, and mice. Although NAD+ replenishing shows promising results in animal models, scientists are still studying how these results can translate to humans.

nmn.com/precursors/what-is-nad

I want a long healthy life, I want to be dancing at a 100 plus. To do that I must beat PD's progression......

[Bolt_Upright]

Thanks Gcf51. I hope you are dancing at 100!

[Gcf51]

I feel a fresh supply is needed, not NAM (a recycled compund which is rate limiting to the production of Sirtuins). There's probably a reason NAM can be further processed to be disposed of in your urine.

fig from https://www.nmn.com/precursors/nmn-vs-nr

[Gcf51]

I am now taking NMN as a NAD+ booster, I believe TTDF (B1) is the basic fuel required healthunlocked.com/cure-par...