Bolt, look what just came through my news feed.
mdlinx.com/news/could-there...
Both a research paper and a research review suggest a potential role of intestinal inflammation and microbiome in the development and/or the progression of amyotrophic lateral sclerosis.
Is it the cause, an effect or a cofactor?? My critical thinking says a cofactor.
Here's the hint that Dr. Sun knows the cause. Sun said she heard about U.S. military veterans who suffered from GI issues while they were serving overseas and later diagnosed with ALS. Several research studies have shown veterans have an elevated risk of developing ALS. Sun said there are still few answers as to why to those who served in the military are at a higher risk of ALS. [It was exposure to nerve agents.]
There was a group of doctors in environmental medicine working very hard on this 20 years ago. I was privileged to call one of them "my" doctor. The doctors and GW vets are dying off. I feel like Sun is studying their research.
The ALS mice were treated with butyrate or antibiotics to investigate the microbiome and neuromuscular functions. They found the mice had significant alteration of the microbiome, decreased intestine mobility and physical stamina before the onset of ALS.
For mice that were treated with BUTYRATE, these decreases took significantly longer to appear, according to the study. The treated mice had enhanced enteric neuromuscular function and showed an altered bacterial community related to AUTOIMMUNITY—changes that demonstrate a link between the microbiome and intestinal mobility.
Is this acknowledgement of an autoimmune process??
Sun said their pioneering research in the microbiome and intestinal dysfunction is getting noticed in the ALS community. Sun and her team are standing on the shoulders of giants. I hope she remembers this.
SE