Results
We found that vitamin D-activating enzyme CYP27B1 identified a subpopulation of astrocytes exclusively in PD patients. CYP27B1 positive astrocytes could display neuroprotective features as they sequester α-Synuclein oligomers and are associated with Lewy body negative neurons.
Conclusion
The presence of CYP27B1 astrocytes distinguishes PD patients and suggests their contribution to protect neurons and to ameliorate neuropathological traits.
Stanford Gloves Development: New Patent Granted Oct 12Parkinson’s Disease: Can Targeting Inflammation Be an Effective Neuroprotective Strategy? 2021
Presentation by Prof R Barker - University of Cambridge: \"Can we repair the brain in PD using cell-based therapies?\"
Mitochondrial uncoupling ; can this help PD, appears maybe Recording now available of presentation by Prof Barker - Cambridge University: \"Can we repair the brain in PD using cell-based therapies?\"
