jimcaster

Thank you for sharing the latest excellent presentation to/from NoSilverBullet. Dr. Barker is an excellent communicator. As Dr. Barker notes, stem cell therapy is not a cure, but it gives me hope.

I appreciate his ideas about two Parkinson’s subtypes and tailoring trials accordingly.

Michel0220 in reply to jimcaster

Thank you very much Jim. It is not a cure but it seems to have the potential to fix you for the next 40 to 50 years which is good enough for me!

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jimcaster in reply to Michel0220

My thoughts exactly.

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hanifab23 in reply to jimcaster

Where is the trial and when

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jimcaster in reply to hanifab23

The upcoming trial which Roger Barker involving Roger Barker will be in the UK. I encourage you to watch the video for more details.

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nedim

Has anyone done Blood Tests to Detect Inflammation? It has been mentioned in this video.

jimcaster in reply to nedim

I have had blood tests done. There are a few markers of inflammation, most notably CRP (C-Reactive Protein). My levels were high.

healthline.com/health/c-rea...

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Kia17

Thank you for sharing Youtube link. The presentation was amazing and answered many questions we may have about the cell-based therapies.

Michel0220 in reply to Kia17

Thank you very much Kia, i’m glad to read that you enjoyed the presentation.

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Biensur

Thank you for bringing Dr. Barker's discussion about cell based therapies to our attention. He gave us insight into methodology, successes and failures along with the difficulties one encounters in clinical trials. Most importantly he gave us hope for the future.

Michel0220 in reply to Biensur

Thank you very much Biensur. Fully agree with you.

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Despe

Michel,

Thanks for sharing Dr. Barker's excellent presentation. It was easy to follow and understand it.

The stem cell therapy he presented is for younger patients. However, I believe several forum members don't fit that category as they are over 70. Most likely, they won't be around when it goes from the trial phase to successful procedure outcome.

Personally, I believe in autogenous stem cell therapy, not embryonic.

Michel0220 in reply to Despe

Thank you very much Despe. Your point about age is unfortunately perfectly correct. We can only hope that stem cell therapies become available the soonest and benefit as many of us as possible.

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Despe in reply to Michel0220

It is my hope, too. Stem cell therapy without age discrimination.

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kaypeeoh

I watched the entire video. I have a problem of losing focus when watching movie-length videos but the 'barking-mad ' Dr Barker kept my interest. He mentioned DAT scans were not helpful but PET scans were helpful when following progress in test subjects. I thought they were essentially the same thing?

I've been long interested in stem cell therapy. In the past I had bone marrow taken from my hip and injected into my Achilles tendon. I read a study that said sq fat has thousands more stem cells per cc when compared to an equal volume of bone marrow. Stem cells are are young calls that haven't yet turned into functional cells. The theory is that stem cells can decide on which type of cell to become based on which type of cell is needed.

I used that idea to treat a dog with bilateral ACL damage. I collected fat from his abdomen and injected it into his stifles (knees). Six months later he was still a working Retriever. He had been on the verge of being euthanized because he could no longer hunt/retrieve.

No cell in the body lasts forever. Our bodies produce new cells as the older cells lose function. But In PD substantia nigral cells are not being produced. So we take L-dopa. Stem cells have the same problem of not lasting forever. If the stems cells die the disease takes over. Dr Barker mentions that his stem cells don't last forever but last many years and can be re-transplanted as needed in the future.

Michel0220 in reply to kaypeeoh

Absolutely. I think he mentioned that the cells live around 40 to 50 years. Good enough for most of us!

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kaypeeoh in reply to Michel0220

Yes but not if I'm planning to live 200 years.

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Michel0220 in reply to kaypeeoh

😅

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Smittybear7 in reply to Michel0220

Why is there an age restriction

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Michel0220 in reply to Smittybear7

I can’t remember for sure but I suspect it is because of the invasive nature of the dopamine cell replacement transplantation. This approach involves injecting new dopamine producing neurons into the part of the brain to replace the dead or dying neurons. I will check with R Barker next time I correspond with him.

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WinnieThePoo

Excellent presentation. One of the best I've seen. Thank you for organising it

Michel0220 in reply to WinnieThePoo

Thank you very much Winnie, I am glad you liked it.

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Propertytyphoon

Another great speaker and looking forward to the next session 👍