Was Mannitol just a hype?

[Farooqji]

Here are the results of double blinded study

frontiersin.org/articles/10...

[alexask]

I don't know what to make of this. I still take a spoonful a day and still think that it restored my sense of smell.

[kaypeeoh]

What I gleaned is at least some of the mannitol crosses the BBB but they couldn't find a reason for it helping with alpha synucleon dispersal. I never tried it only because my card was rejected. Now I'm glad only a little bit of money wasted. That leaves more to spend on FIR and Red light photomodulation.

[Hidden in reply to kaypeeoh]

What is FIR?

[kaypeeoh in reply to Hidden]

Far InfraRed

[Hidden]

It’s an anti inflammatory Inflammation makes PD (and all diseases) worse. There is some evidence of it being beneficial to the gut biome.

I KNOW it improved my sense of smell bc products I had no idea had fragrance I could suddenly smell.

Trehalose is another one worthy of researching

I use it a few days a week.

[Skydome]

Came across this tweet:

Series of words.

[Astra7]

What a small study. Only concluded that you can take 18g a day without problems, but didn’t seem to look at whether it worked or not. Inconclusive I reckon and at odds with my personal experience, although I’m currently not taking due to gas issues!!

[Smokeypurple]

Seems to me that as mannitol can be taken without adverse effect other than gas (so I take it at night...) it's one to try out in case you're one of the ones that benefit...

[gwendolinej]

If you’d seen my husband one week after starting on mannitol, they’d believe it can work (for some obviously). It was amazing and continued to be for 18 months. He just had a minor blip and spent a few weeks in hospital. He is back on track now. The neurologist kept him on the mannitol while he was in hospital. See my post.

Gwendoline