Professor Thomas Borody Interview: Comments on Trial Designs and Ethics of Clinical Trials

[Bolt_Upright]

Dr Borody, as most of us know, is the Godfather of FMT (and a genius). The first 6 minutes of this interview are dynamite, but I set it to start at 5:50 to queue up something I think is very important: The idea that a single substance is going to cure a complex condition is not likely. So why do they keep doing trials with single treatments and then chocking them up as failed treatments? My high school degree says we should be looking at combinations. (please do also watch the first 5 minutes. Dr Borody slays!):

youtu.be/POfIMGS2D6A?t=350(Not working as expected?)

[Despe]

Did you ever wonder why one has to have the jab if there is early treatment available, Bolt?

Didn't you know about IVERMECTIN???

[kaypeeoh in reply to Despe]

Didn't the doctor who first popularized treating COVID with ivermectin ultimately die of COVID?

[gaga1958 in reply to kaypeeoh]

No, if you are referring to Dr Pierre Kory. He did get covid but did not die and is fine. Kory is the dr that gave testimony at the U.S. Senate Committee on Homeland Security and Government Affairs which you can find on youtube unless its been removed. There are a number of other doctors that tout ivermectin so I'm not sure which other one you may be thinking of. ( dr Vladimir zelenko, dr mark mcdonald, dr hector carvallo,

dr mary bowden, dr robert karas, dr Louis Safranek, dr Paul Marik, and many others)

[Despe in reply to kaypeeoh]

Not that I am aware of!

[Bolt_Upright in reply to Despe]

I really did not look at the video as being about Ivermectin. I look at it as about:

1: The stupidity of doing trials on single medicines, when often time it takes a combination.

2: The immorality of having a control group get no treatment at all. Better to compare known treatments.

I knew about Ivermectin. I don't really have an opinion on it. I am not getting vaxxed.

[park_bear in reply to Bolt_Upright]

When patients have any kind of serious illness the control arm is standard of care, not placebo.

There have been occasions when a treatment consists of two drugs in a single pill. Augmentin comes to mind.

[Bolt_Upright in reply to park_bear]

I have to politely disagree on this one my friend. I must have looked at over 50 clinical trials in the last 8 months and read the methods. One group gets the drug, the other gets a placebo. Starch capsule or some such. Serious illnesses like PD and AD.

Also did a quick search and found "The ethics of using placebo in randomised controlled trials: a case study of a Plasmodium vivax antirelapse trial" ncbi.nlm.nih.gov/labs/pmc/a...

It also seems like every trial I have looked at is a single medicine. I guess what drove me to share this video and this concern is I was reading abut how some supplement (I can't recall what it was at the moment) was being determined as not helpful in PD based on the trials that had been done. The ones I looked at were single medicine trials. I'm not trying to sell hopium, but think people should hold onto the thought that just because something does not succeed in a single supplement/medicine trial does not mean it might not work in combination with something else.

Here is more reading: Placebo versus Best-Available-Therapy Control Group in Clinical Trials for Pharmacologic Therapies ncbi.nlm.nih.gov/labs/pmc/a...

FDA Suggests Use of Placebo is Necessary Only in Certain Types of Oncology Trials biospace.com/article/fda-su...

Are Placebos Ethical In Ebola Trials? forbes.com/sites/judystone/...

I could be wrong. I do only have a high school degree (I'm not even sure if I should be capitalizing the H and S in high school). I just figure we are trying to Cure PD so anything to make us think about stuff like this could be helpful.

[Despe in reply to park_bear]

I agree, PB.

[kevowpd]

Post this junk to Facebook. Nothing to do with PD.

(And by the way, there are many CTs that used multiple compounds in the treatment arm)