I wanted to give this forum an update on my participation in the clinical trial at the University of Texas in Houston. I was reluctant to comment before the study was completed but was compelled by my wife to do so. It has been nearly one month since my first infusion, but my family has witnessed some clear improvements.
The first thing that they noticed was my freezing has completely stopped. The next biggest changes are that I no longer have any tremors, my rigidity has lessened, and my gait has improved where I no longer drag my right leg. What I noticed, is my speech has improved along with my vision has become clearer, and my jaw and tongue no longer quiver when I open my mouth.
I only had a 33% chance of receiving the real stem cells on the first leg, so I wasn't expecting anything, but I did notice after 2 two weeks I started feeling a little flushed each day. My blood pressure remained steady, and I temperature was normal, but I remember the Dr. asking me during the infusion how I was feeling and if I felt flushed. Just an observation.
So if I got the Placebo, all I can say is sign me up for another. I am patient 37 out of 45 and I am in the last group. Group 1 has already received their 2nd infusion and mine is scheduled at the end of February. I remain cautiously optimistic and hopeful that this study will prove to be a viable therapy for those who have any form of neuro-degenerative disease, until a complete and effective cure has been has discovered.
Bone marrow extraction from a healthy donor was obtained by aspiration under local anesthesia. Testing was performed using FDA-approved licensed kits by Gulf Coast Regional Blood Center. MSCs were expanded using a Terumo Quantum Bioreactor29 by the Center for Cell and Gene Therapy of Baylor College of Medicine under current Good Manufacturing Practices designated by the FDA. The total quantity of allo-hMSCs was reached in 3 passages. Thawing was initiated on infusion day, and allo-hMSCs were aliquoted into a 250-mL transfer pack with 5% buminate. Release tests were performed on the pooled cells (purity, viability, cell dose, and microbiological testing).
Just a guess, but stem cells are supposed to migrate to wherever they're needed. I had bone marrow injected into my Achilles tendon to heal a tear. In Mexico they inject marrow into a vein in hopes it will migrate to the injured area.
The treatment with bone marrow was 3 years ago. It never helped but I went to a podiatrist who diagnosed the problem. I had a Heglund's deformity, in essence a tumorous growth jutting from my Achilles tendon. Surgery to remove cured the problem.
Sounds a really positive outcome and great that you have achieved this improvement. Encouraging that it is an infusion and a non invasive type of treatment. Please keep us updated.
Thanks for sharing. Please keep this group aware on the progress on the trials. May your results continue to be positive and your progression of PD slowed, even stopped. Look forward to the write up of this one.
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