A point that should be made: The plaques in your bloodstream are mostly cholesterol and calcium, but the doctor recommends a lower cholesterol diet and doesn't mention the calcium.
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Gcf51
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The body needs vitamins K and D, plus some cofactors, to get calcium out of the bloodstream into the bones. Otherwise it gets deposited in the arteries causing hardening of the arteries and not in the bones, resulting in osteopenia/osteoporosis. See my writing here for further detail:
What You Need to Know to Reduce Risk of Hip Fracture and Cardiovascular Disease
This is not about calcium supplementation. It is about conditions within the neuron that control the concentration of calcium. From the study text:
" Our results show that upon stimulation there is no further change in the distribution of alpha-synuclein throughout the synaptosomes (Supplementary Fig. 5), suggesting that normal physiological calcium concentrations are sufficient to induce alpha-synuclein clustering."
Moreover, it is not all clear what this clustering at the synapse has to do with Alpha synuclein toxicity. The toxicity is due to interference with the mitochondria, the Golgi body, and the endoplasmic reticulum, which are not located at the synapse.
A point that should be made: The plaques in your bloodstream are mostly cholesterol and calcium, but the doctor recommends a lower cholesterol diet and doesn't mention the calcium.
At the end, the article proposes that calcium-channel blocker medications might help deter PD. Has anyone tried this? Is anyone here already on a calcium channel blocker and, if so, were you on it before you had PD? [If someone had been taking a calcium channel blocker for many years before diagnosis, this tends to disprove that hypothesis]
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