Good stuff on ketosis and ketone esters. Might need to add to the stack again 
Focused on PD and AD:
ncbi.nlm.nih.gov/pmc/articl...
Summary and relevance statement
Most neurodegenerative diseases, including AD and PD, are associated with the key pathologies of mitochondrial dysfunction, neuroinflammation, and glucose hypometabolism and/or insulin resistance. Currently, there are no effective therapies for slowing the progression of either AD or PD. By addressing these core pathologies (and likely others), endogenously or exogenously induced ketosis might prove to be a novel and useful adjunctive therapeutic for these neurodegenerative conditions.
Focused on AD:
ncbi.nlm.nih.gov/pmc/articl...
Conclusion
KME-induced hyperketonemia is robust, convenient, and safe, and the ester can be taken regularly as a food supplement without need to change the habitual diet.
In treatment of TP’s long-standing AD dementia, KME-produced repeated diurnal elevations of circulating βHB levels were clearly effective, during the 20-month study, in improving behavior, and cognitive and daily-activity performance. The physician-caregiver noted that performance seemed to track plasma ketone concentrations, with conversation and interaction declining as levels fell toward baseline. From requiring almost constant supervision, TP became much more self-sufficient on KME. However, generalizability of TP’s partial improvement during KME treatment (it cannot be called a “cure”) remains to be determined by appropriately designed case-control studies.
Has anyone tried Ketone Ester to improve PD symptoms?
Low Magnesium and PD
The key to ketosis and neuroprotection? NAD+???
