Finally meet my MDS after my FUS surgery - Cure Parkinson's

Cure Parkinson's

26,583 members27,897 posts

Finally meet my MDS after my FUS surgery

Markbit profile image
35 Replies

I went to see my MDS two days ago, 4 months after my PTT FUS surgery and he was really happy with the results. He opposed initially and tried to convence me to go through DBS, but he was very pleased with my evolution. He advised me i should up l-dopa a bit, what i'm trying adding mucuna, and i feel a bit more stable. In the end he agreed that this kind of intervenction would be the future for the treatment as is much less invasive than DBS, and also confident to me that he had already sent one of his patients to Spain to be evaluated and see if was suitable for FUS, althoug he said there is not enough data avaliable data for the moment. But things are changing.

Written by
Markbit profile image
Markbit
To view profiles and participate in discussions please or .
Read more about...
35 Replies
Resano profile image
Resano

"In spiritual terms, the Source of all things is inside all things" (Dr Jeanmonod: Consciousness, a Riddle and a Key in Neuroscience and Spirituality, 2011)

jimcaster profile image
jimcaster

Congratulations, Marco! I hope you continue to improve.

Markbit profile image
Markbit in reply tojimcaster

Thank you Jim. Hoping for that too

Smittybear7 profile image
Smittybear7 in reply toMarkbit

Wishing you continued success.

Despe profile image
Despe

Congrats, Mark! Hope your improvements will continue. I believe PTT is the present and the future of PD.

Markbit profile image
Markbit in reply toDespe

At least my MDS liked and approved. He is one of the top neuros in my country.

JANVAN profile image
JANVAN in reply toMarkbit

Your country >>> is that Brazil ?? Than you should also heard about that neurology professor, Dr. Coimbra.....

And are you planning to do other therapy ? Because a few days ago there was a very interesting post about a good designed Chinees study about gut and Parkinson !!

Just One special thing for me, in that study, they did it only with 12 patients,......

that's not such a big number, so the power of this study is not so big...........

(sorry for the not so nice "formatted" article, but I think, you will get out of it)

Science Focus - the home of BBC Science Focus Magazine

Sign up to our newsletters

NEWS

FUTURE TECH

NATURE

SPACE

HUMAN BODY

EVERYDAY SCIENCE

PLANET EARTH

Home Science news Scientists identify gut bacteria linked to neurodegenerative conditions

Scientists identify gut bacteria linked to neurodegenerative conditions

6 issues for £9.99 when you subscribe to BBC Science Focus Magazine

In a study of the worm C. elegans, the team found bacteria species linked to the development of the conditions, and others that can counteract the effect.

By Sara Rigby

Published: 07th May, 2021 at 10:51

Share on Facebook

Share on Twitter

Share on Reddit

Email to a friend

Researchers have identified gut bacteria species that appear to play a role in the development of neurodegenerative diseases such as Alzheimer’s, Parkinson’s and motor neurone disease.

Previous research has shown a link between the conditions and changes in the gut microbiome, but among the thousands of species that live there, it wasn’t easy to identify which ones have an effect. Now, a team based at the University of Florida, USA, have not only identified the harmful bacteria, but have also shown that certain other bacteria species can produce compounds that counteract the effect.

“Looking at the microbiome is a relatively new approach to investigating what causes neurodegenerative diseases. In this study, we were able to show that specific species of bacteria play a role in the development of these conditions,” said Dr Daniel Czyz, assistant professor at the University of Florida.

Read more about neurodegenerative illnesses:

‘Game-changing’ swab test could revolutionise Parkinson’s diagnoses

New device could allow you to control a computer with your inner ear muscle

Nanoparticles could deliver Alzheimer’s treatments to the brain

“We also showed that some other bacteria produce compounds that counteract these ‘bad’ bacteria. Recent studies have shown that patients with Parkinson’s and Alzheimer’s disease are deficient in these ‘good’ bacteria, so our findings may help explain that connection and open up an area of future study,” he said.

Neurodegenerative disorders result from proteins building up in tissue in the body. These accumulations of proteins can interfere with cell functioning.

The team studied the link between gut bacteria and neurodegenerative disease in a worm called C. elegans. When they were infected with the harmful bacteria, proteins began to build up in their tissues.

“We have a way of marking the aggregates so they glow green under the microscope,” said Czyz. “We saw that worms colonised by certain bacteria species were lit up with aggregates that were toxic to tissues, while those colonised by the control bacteria were not.”

Normal C. elegans (left) compared with worms infected with pathogenic bacteria © University of Florida

Normal C. elegans (left) compared with worms infected with pathogenic bacteria © University of Florida

The worms also lost mobility. “A healthy worm moves around by rolling and thrashing. When you pick up a healthy worm, it will roll off the pick, a simple device that we use to handle these tiny animals,” said Alyssa Walker, lead author on the paper. “But worms with the bad bacteria couldn’t do that because of the appearance of toxic protein aggregates.”

The team hope to carry out further experiments in higher organisms, and then eventually in humans.

What is dementia?

Some 850,000 people are estimated to be living with dementia in the UK, and that’s expected to rise to two million by 2050.

Dementia describes the symptoms that someone experiences as a result of a brain disease. Such symptoms can include memory loss, mood and behavioural changes, and difficulties with thinking, problem-solving and language. More than 100 diseases can cause dementia, each with slightly different symptoms.

The most common cause of dementia is Alzheimer’s.

Discover more about dementia:

And here is that link to the study >>>

Redirect Notice

Looks like you clicked

ncbi.nlm.nih.gov/pmc/articl...

A lot of greetings from Switzerland !

Markbit profile image
Markbit in reply toJANVAN

Hi Janvan. Nop, i'm from Portugal. I have been doing some readings from Dr. Cícero Coimbra from some years ago (that´s why i do take 5000 IU's of vitamin D on a daily basis). I believe Parkinson's is closed related to the gut, some studies show strong links, but i have read so many studies in the past years that i stopped believing in magic pills and miraculous bacterias. I believe that the disease can be controlled (to a certain point) with a lifestyle change, avoiding stress, good diet, exercise and socialization, and every tiny thing we do helps us to get a better life. Most important is to give value to the life we have, and make good choices, informed choices. I believe i have been lucky managing my disease, but i also wanted to be lucky... a lot.

Greetings from Portugal also!

artinson profile image
artinson

Happy this is working out for you! Congratulations.

Markbit profile image
Markbit in reply toartinson

Thank you!

Zella23 profile image
Zella23

So pleased you’re doing so well, great news!Thanks for updating us really good to hear of your journey and excellent improvement.

Markbit profile image
Markbit in reply toZella23

Thank you Zella. It's good to fell this way 😄

Missy0202 profile image
Missy0202

I am so encouraged for you, and for all of us waiting in the sidelines. Looking forward to your next great report! YAH for you!

b-bobble profile image
b-bobble

Is this the same procedure that is performed in Switzerland? What improved for you?

Markbit profile image
Markbit in reply tob-bobble

Yes, i did the procedure in Switzerland. Improvements, see for yourself.Me in xmas before surgery

youtube.com/watch?v=jYOU7KS...

4 months after FUS, in the morning before taking any meds

youtu.be/vNchb2xaW-k

youtu.be/N4jDWw19cl4

youtu.be/6ETTQBint4E

You will see some diferences between my treated and my untreated side.

Yeswithasmile profile image
Yeswithasmile in reply toMarkbit

Hi Markbit

I am new to posting here but wanted to say I watched your clips and congratulations!! You must be very pleased with the outcome! Thank you for posting. It is really encouraging.

Markbit profile image
Markbit in reply toYeswithasmile

Thank you. It's not like no disease, but way better than before.

Yeswithasmile profile image
Yeswithasmile in reply toMarkbit

Yes. I could see that you were greatly improved. I think you were very brave and it paid off. Really so pleased for you.

ConnieD profile image
ConnieD in reply toMarkbit

Yes you are so improved, do you feel like you need any medicine really? Did you have to shave part of your head, or did your hair grow quickly back?

Markbit profile image
Markbit in reply toConnieD

Hi Connie. Yes, i still need my meds to function properly, especially after 11 a.m, but more reduced now. I still have PD. I did shaved my head, but my hair growed really fast. I had to cut it two or three times already after the surgery.

ConnieD profile image
ConnieD in reply toMarkbit

You wouldn’t even know you had PD anymore from your video’s, congratulations! So happy to see your feeling well!😊

JANVAN profile image
JANVAN in reply toYeswithasmile

Hi Marco ! Can you send the -xMas Video before the operation again please here or to the facebooksite. Or in another format, because I can't open it.....The other ones or no problem ....!

Thanks in advance, Jan.

Markbit profile image
Markbit in reply toJANVAN

Search for Marco Serrabulho on youtube and probably you will find my channel. My videos are there.

in reply toMarkbit

Congratulations on your dramatic improvement! Thank you for sharing these videos with us. They are wonderful to see, just wonderful!

Despe profile image
Despe in reply toMarkbit

Mark,

You are absolutely two different people! Your PTT was short of a miracle, so proud of you.

Markbit profile image
Markbit in reply toDespe

Thank you!

One more thing i discovered i can do now 😄

youtu.be/xGr91YHFPUg

Despe profile image
Despe in reply toMarkbit

That's amazing, I can't even do that. Need a funnel. :)

My husband had cardiac ablation for tachycardia back in 2011, and he is doing great, no more arrhythmia! Ablation does work.

Markbit profile image
Markbit in reply toDespe

Yes it does, for sure 😀

b-bobble profile image
b-bobble

Not able to playback the before video yet. Looking forward to seeing it. Thank you for the videos.

b-bobble profile image
b-bobble

Saw it. What a difference. Very encouraging. Thank you.

delboy381 profile image
delboy381

Nice to see your progress to the old you, I mean without pd. You mentioned that clinic in Switzerland have a some kind foundation that they help with financial especially young people?

Markbit profile image
Markbit in reply todelboy381

Yes they have, it was created by Prof. Jeanmonod. Please contact them for more details.

delboy381 profile image
delboy381 in reply toMarkbit

Thank you.

Chriscrozer profile image
Chriscrozer

Hi there I am considering FUS and it's heartening to hear your results are good so far,.....can you tell me where you went for the treatment or to which doctor... thank you

Markbit profile image
Markbit in reply toChriscrozer

Hi. I went to Sonimodul in Switzerland with Prof. Jeanmonod team. They are great and probably the most experienced team in the world with this tecnique.

Not what you're looking for?

You may also like...

I saw my first neuro after over five years

Today I saw the MDD who diagnosed me in august 2017. Before him I saw other doctors who could not...
ion_ion profile image

DBS truly reversible?

Hi all, In all the DBS vs FUS posts the argument is that DBS is reversible. The two people I know...
lenamm profile image

45 mins conversation with dr. Jeanmonod regarding FUS

Hi all! I just spoke with dr. J about my situation. In my case he said the PD looks very easy...
ion_ion profile image

Results on FUS PTT surgery for PD

UPDRS off-medication postoperative score revealed percentage reductions of the mean of 84% for...
lenamm profile image

FUS PTT Surgery. 6 months update

After 6 months things look bit more stable. I still have some issues, and sometimes it is still...
Markbit profile image

Moderation team

See all
CPT_Aleksandra profile image
CPT_AleksandraAdministrator
CPT_Anaya profile image
CPT_AnayaAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.