HCL and off's

[aatje]

It is possible that because of Thiamine HCL the off periods last longer, occur more often and become more intense? I don't know what to do right now. I'm hoping somebody can help me.

[dadcor]

Yes, I would take a rest from it for min 10 days, and then start again reducing the current dose by half..

[aatje in reply to dadcor]

Thanx! 🙏🌺

[chartist in reply to aatje]

I agree with dadcor. Take notes, if you follow dadcor's advice. You're looking for symptom improvement while you are off B-1. If you notice symptom improvement, then your current dose is likely high according to what Dr. Costantini told us. The sooner the symptoms improve, the closer you are to your ideal dose is what Dr. C told us and it so far has been working out that way. If it takes a few days or more to see improvement while off of B-1, he has said that your current dose is too high and a larger dose reduction is likely needed. If you can remember pretty accurately and you did get initial improvement from B-1, how soon did you notice benefit after starting B-1? How soon did you notice a decline in any benefit?

Have you ever noticed any improvement that you attribute to B-1? How did you decide on the dose that you are currently using and what is that dose? How much do you weigh? Are your symptoms normally mild, moderate or severe? If you initially noticed improvement, but then those improvements started declining and your symptoms started to worsen, this is again an indication that your dose is too high. The 10 days that dadcor mentioned should be sufficient to let your B-1 level drift back to its native level. If you see no improvement at any time while off of B-1, it is possible you are not a responder to B-1. Some people do not respond to B-1, but the majority of people do. Dr. C said a dose that is too low will likely offer no benefit at all, but it should not worsen symptoms. A dose that is too high can actually worsen symptoms to worse than has been previously seen before. Any increase in symptoms from a dose that is too high have always returned to normal once the dose is lowered or stopped.

Here is a link to HDT/ B-1 information that should answer most questions you might have about HDT/B-1 :

healthunlocked.com/parkinso...

Keep us updated on how you do. Answering the questions above will make it easier for other forum members to make suggestions to you.

Art

[aatje in reply to chartist]

Thank you for your comprehensive answer. It takes time to answer all the questions in your response. But I will certainly try to provide answers.

🌺🙏

[gaggs8]

I have started taking Bisolvon, for off periods works so far.

[aatje in reply to gaggs8]

But Bissolvon is against coughing and phlegm in the throat.

[gaggs8 in reply to aatje]

There ha s been studies in America with the drug Bromhexine for off time in Parkinson's it was on this site I read it. So I use it when Sifrol wears off just one tablet is enough. There were other people saying Benadryl works too but it did not for me. I like bisolvon.

[aatje in reply to gaggs8]

I'm sorry I didn't take you seriously. It is worth a try. Thank you.

[aatje in reply to gaggs8]

With search I cannot find anything about bisolvon or bromhexine on this site.