Might this be relevant for some PwPs?
An engineered enzyme that targets circulating lactate to alleviate intracellular NADH:NAD+ imbalance.
Mitochondria significance : circulating l... - Cure Parkinson's
Mitochondria significance : circulating lactate
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aspergerian13
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Lactate, GSH, etc inPD:
Parkinson’s disease-related DJ-1 functions in thiol quality control against aldehyde attack in vitro. [Glutathione, GSH]
ncbi.nlm.nih.gov/pmc/articl...
Metabolic Investigations of the Molecular Mechanisms Associated with Parkinson’s Disease. Lactate. Pmc. 2017.
ncbi.nlm.nih.gov/pmc/articl...
Cerebrospinal fluid lactate and pyruvate concentrations in patients with Parkinson's disease and mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS). 1997. Lactate. Pmc.
ncbi.nlm.nih.gov/pmc/articl...
Parkinson’s Disease: Biomarkers, Treatment, and Risk Factors. 2018. Lactate. Pmc.
ncbi.nlm.nih.gov/pmc/articl...
Manifestations and Outcomes of Patients with Parkinson's Disease and Serious Infection in the Emergency Department. 2018. Pmc. Lactate.
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