“Researchers believe all these functions of SAM-e contribute to its role in beating depression. When taken as a supplement, sam e depression benefits include beating depression naturally without all the side effects of conventional drugs”.
Studies Show Beating Depression Naturally... - Cure Parkinson's
Studies Show Beating Depression Naturally with SAM-e is Superior to Antidepressant Drugs
I used SamE for a while and it worked quite well. Then not so well. After many years of ups and downs, starting C/ L took care of my depression 100%. This doesn't happen for everyone but I have met others who have had the same experience.
Bocopa Monnieri extract is equally good
I bought this Sam-e last year:
vitacost.com/vitacost-syner...
I decided not to take any after reading the warning on the box: "Individuals with Parkinson’s Disease should not use Sam-e".
Although I had found lots of info saying it was good (prior to ordering it...), here is some of the warnings I found afterwards:
rxlist.com/same/supplements...
SAMe can chemically change levodopa in the body and decrease the effectiveness of levodopa. Taking SAMe along with levodopa might make Parkinson's disease symptoms worse.
ncbi.nlm.nih.gov/m/pubmed/1...
L-dopa has been shown to deplete the concentration of SAM, and SAM has been found to induce PD-like motor impairments in rodents; therefore, an excess of SAM-dependent methylation may be associated with Parkinsonism
You just can't win! One study says it's good for PD and then another study says it can worsen symptoms! You might beat the depression, but then your other symptoms might worsen, ugh!
Art