Mannitol

[ruff1]

Anyone using mannitol to help with their Parkinson’s symptoms?

[Xenos]

I do...

[ruff1 in reply to Xenos]

Have you noticed a difference?

[Xenos in reply to ruff1]

Not really, but I still take it, hoping that it slows down the progression of the disease. And maybe it does...

[Astra7]

Yes. 1 tsp in my coffee every morning. I believe it helps with brain fog and stumbling speech, as well as sense of smell.

[ryanJames1]

I have 1/2 tsp twice a day

[ruff1 in reply to ryanJames1]

Have you noticed a difference?

[ryanJames1 in reply to ruff1]

Yes absolutely definitely helps !

[LAJ12345]

My husband does. I’m unsure if it helps with all the other changes in diet, supplements it is hard to see what causes what.

One thing I am wary of is that it can feed bacteria. My husband has had a faeces test which showed an overgrowth of corynebacterium amylatum which is often found in PD people and it is not a good bacteria. This bacteria feeds on mannose and not all bacteria do . Not sure if his is due to taking the mannose or whether he had it already. He stopped taking mannose for a while but then restarted as we decided that since it eats glucose too the small amount of extra mannose shouldn’t matter. Not sure if we are right or not 😕

[dangilio]

I have read that mannitol is not recommended for those who take anti-coagulant drugs. I would like my mom to try it, but she is also taking cardio aspirin as an anti-coagulant. Are any of you taking anti-coagulant drugs?

[Motherfather in reply to dangilio]

well im taking an asprin every day dangilio i have been taking one every day also mannitol one teaspoon twice a day.no problems so far.maybe give it a try for awhile.regards.

[dangilio in reply to Motherfather]

do you take aspirin as an anticoagulant?

[Motherfather in reply to dangilio]

no dangilio i have 1 asprin coated 1 caustat and 1 salpraz thats for a dudenal ulcer the asprin is for thining the blood .

[dangilio in reply to Motherfather]

thining the blood mean anti coagulation.. or not?

[Motherfather in reply to dangilio]

yes you could say that dangilio.

[Fed1000]

I have recently been using mannitol, 20 gr. per day. it is a sweetener. They are packs of 10 gr. each that you can easily melt in water, milk, tea etc. My mannitol it is produced by an industry of northern Italy. I do not know if it stops or slows down the progression of Parkinson's, it would be too good. What I can tell you is that it provides a sense of general well-being, both physical and mental. There are not side effects except for a gas production. It can be taken forever. Given that the product is harmless, you could try it quietly.

[dangilio in reply to Fed1000]

hi fed1000, are you italian? i'm from reggio emilia..where do you take mannitol ?

[Fed1000 in reply to dangilio]

Hi dangilio, I'm from Pisa. The product is called "physiomanna LaxDepur" produced by Iuppa Industriale srl - Alice Bel Colle (AL). If you have difficulty let me know that I can recover a telephone number. Regards.

[Coot18]

Is this the same mannitol you are taking?

en.wikipedia.org/wiki/Mannitol

if so, it makes no mention of neurological use

unless reduction of cranial pressure benefits some how

am I missing something?

[danfitz in reply to Coot18]

It is believed to encourage the autophagy of alpha-synuclein. Other alcohol sugars are also believed to have the same effect.

[Cons10s in reply to danfitz]

So are you saying Wine is good? Yeah!

[Hidden in reply to Coot18]

Mannitol is a sugar alcohol or polyol and it has other known effects that aren't outlined in the Wikipedia article. Mannitol acts as a prebiotic also and this may be an important method of action for its use in PD that is not often mentioned. I wrote a little about that aspect here:

healthunlocked.com/parkinso...

Art

[Cagey84]

Hi - here is the Clincrowd decentralized trial on Mannitol - clinicrowd.info/parkinsons-... . When you register you get a lot of info on mannitol and PD, guidance on dose, suppliers etc

[fullinspections in reply to Cagey84]

tried mannitol for 6 months 2 teaspoons per day had no results . if it works for you it will not hurt best of my knowledge it is just a sugar substitute

[dreem]

it does seem to help me some. I notice the difference if I stop