Thiamine diphosphate reduction strongly correlates with brain glucose hypometabolism in Alzheimer’s disease

[Kia17]

Thiamine diphosphate reduction strongly correlates with brain glucose hypometabolism in Alzheimer’s disease, whereas amyloid deposition does not

The underlying mechanism of brain glucose hypometabolism, an invariant neurodegenerative feature that tightly correlates with cognitive impairment and disease progression of Alzheimer’s disease (AD), remains elusive.

ncbi.nlm.nih.gov/pmc/articl...

What is brain glucose hypometabolism?

google.co.uk/amp/s/www.psyc...

[park_bear]

The psychology today article makes it seem like there is agreement that insulin resistance causes Alzheimer's. There is no such agreement. There is convincing evidence that amyloid is a response to infection. However, there is not consensus on that point either.