Vitamin B3 and PD

[Kevin51]

Helpful post today on this topic from Science of Parkinson's

scienceofparkinsons.com/201...

Supports previous comments on this (eg Sylvestrov).

Just popped a Niacin (non flush) tablet

[saraoutwest]

Interesting. I love simons work. Would like to see him investigate thiamine!

[Hikoi in reply to saraoutwest]

Did you know Simon is an NZer now working in the UK? I find his posts really interesting and useful.

[Kevin51 in reply to saraoutwest]

Yes. I take about 1gm of Thiamine per day - seems to deal with the fatigue I used to get a lot - but it is hard to be certain and it would be great to have some more science on that.

[Gioc]

very interesting thank you

[rideabike]

Interesting study and thanks for posting. I copied the list of foods niacin is in because the daily levels recommended are probably lower than any supplement you can buy (16mg men/14 women). My B-Complex has 50 mg in it. Too much to take daily.

Foods that have naturally high levels of niacin:

1) Turkey. 1 breast: 101 mg (over 100% of your daily value (DV))

2) Chicken breast. 3 oz: 8.9 mg (44% DV)

3) Peanuts. 1 cup: 21.9 mg (over 100% DV)

4) Mushrooms. 1 cup: 7.6 mg (34% DV)

5) Liver. 1 slice: 11.9 mg (60% DV)

6) Tuna. 3 oz: 11.3 mg (56% DV)

7) Green peas. 1 cup: 3 mg (15% DV)

8) Grass-fed Beef. 3oz: 7.6 mg (36% DV)

9) Sunflower seeds: 1 cup: 3.8 mg (19% DV)

10) Avocado. 1 whole fruit: 3.5 (17% DV)

[Kevin51 in reply to rideabike]

I was struck by the comment that people with PD have a chronic Niacin (B3) deficiency. The clinical trial will be giving PWPs 250mg and reporting in 2019. I have taken 100mg (non-flush) Niacin on and off for the last year with no ill effects and will be more on than off after reading this post.

[rideabike in reply to Kevin51]

Thanks Kevin...must read the study more carefully. Was wondering how such a small amount daily would work.

[Hikoi]

i contacted the aurhor of the science blog and he has had a number of requests for one on thiamine and plans to write one soon.