Vitamin B12 Supplements May Help Slow Parkinson’s Progression, Study Finds

[Farooqji]

Low levels of vitamin B12 in patients in the early stages of Parkinson’s disease are linked to faster motor and cognitive decline, suggesting that vitamin supplements may help slow the progression of these symptoms, a study has found.

The study was supported by funding from the Michael J. Fox Foundation, and gifts from the Ko and Tsu family and William and Mary Ann S. Margaretten.

parkinsonsnewstoday.com/201...

[sunvox]

Great find! Thanks for sharing. I have another condition called recurrent apthous stomatitis where I get terrible sores in my mouth that are painful, and I have been looking my whole life for some relief when I found this:

ncbi.nlm.nih.gov/pubmed/260...

But since I am always curious about my primary illness that is caused by "misfolded" proteins" that lead me to this:

ncbi.nlm.nih.gov/pubmed/295...

ncbi.nlm.nih.gov/pubmed/282...

And your study is simply one to add!! Thanks again!

Joe

[faridaro]

The problem is that there is no worldwide consensus on minimum acceptable B12 levels.

"In Japan, minimum recommended blood levels of B12, 500 pg/ml (Jpn. J. Psychiatry Neurol. 1988 Mar:42(1):65–71), are more than twice the minimum acceptable levels in the U.S., 200 pg/ml ( nlm.nih.gov)"

So, normal range in US would probably be considered as moderate deficiency in Japan and that's why so many people have undiagnosed B12 deficiency.

[jimcaster]

Thanks for sharing this. It sure seems like heavy doses of B vitamins, particularly B1, B3, and B12 can be really helpful. As has been pointed out in other posts, we can't just rely on standard blood serum test results. We need to know whether we have vitamin deficiencies at a cellular level.

[Hidden in reply to jimcaster]

Jim,

Don't forget B-2 / Riboflavin!!!!!

ncbi.nlm.nih.gov/pubmed/294...

ncbi.nlm.nih.gov/pmc/articl...

ncbi.nlm.nih.gov/pmc/articl...

B-6 has also shown itself to be useful in PD, but dosing can be very critical for some.

Art

[jimcaster in reply to Hidden]

Agreed. Thanks for including B2 and the citations!