THIAMINE : STOP

[ecurb]

After my reaction to Thiamine, after taking 250 mg x 4, I tried a second time a day later with 1 250 mg tablet which gave me same result. I waited for another day taking half a 250 mg tablet. I woke in middle of night with pins and needles running through body and practically unable to move. I managed to swallow one quarter of a Leximil tablet which allowed me to go back to sleep. I became awake around 6 am still under the effect of Leximil all day only being woken by my wife every 2 hours to take a Modopar 125.

I have decided to stop taking Thiamide for the time being. I am disappointed because the favourable posts recently had built up my hopes.

[aspergerian]

Thank you for important feedback. We all might consider observations by William J. Walsh, PhD:

walshinstitute.org/biochemi...

[MBAnderson in reply to aspergerian]

Good post. For those dismissive of supplements.

“Even with an ideal diet, most of us have certain nutrients that are at very low levels with many times the RDA required to achieve a healthy balance.

The brain is a chemical factory which produces serotonin, dopamine, norepinephrine, and other brain chemicals 24 hours a day. The only raw material for these syntheses is nutrients, namely amino acids, vitamins, minerals, etc. If the brain receives improper amounts of these nutrient building blocks, we can expect serious problems with our neurotransmitters.

Most neurotransmitter problems appear to be genetic or epigenetic in nature and involve abnormal absorption, metabolism or storage of key nutrients. Nutrient therapy can be very potent and can avoid side effects, since no molecules foreign to the body are needed. This therapeutic approach may eventually eliminate the need for most psychiatric medications.”

[MBAnderson in reply to aspergerian]

I've read through the website and find it really quite impressive. It makes a strong case for the role of nutrition/supplements in one's brain chemistry. Have you bought the book, Nutrient Power? It's only $15 so I'm tempted.

[aspergerian in reply to MBAnderson]

Walsh's Nutrient Power is on my next-up book list.

[sunvox]

E - Were you taking thiamine hcl tablets or some other form? Thanks - Joe

[Hidden]

So sad you had to STOP. Now you must continue with Parkinson's symptoms and Parkinson's progression.

[park_bear in reply to Hidden]

Let us not go overboard here. Everyone is different. What works for one may not work for another. There are a number of different interventions that are reported to improve Parkinson's and this is only one of them.

[Syncletica in reply to Hidden]

RoyProp: Your posts are encouraging. What PD symptoms have improved with T-HCL intervention. Tremors? Rigidity? ad infinitum..

Thank you for sharing.

[Hidden in reply to Syncletica]

See my Profile. All symptoms improved to a greater to lesser degree. Started w/ mega-benfotimin. Doc Costantini put me on T-HCL and almost immediately, no constipation. I am still looking for improvement from tremor.Doc said 1 -2 months but I am into my 6th week

[stepan13 in reply to Hidden]

I am into my 6th week too. 2000 morning, 2000 evening with food

[Parkie- in reply to stepan13]

Hello Pachikov. I just saw that you were in 6th wk of 4000 daily thiamin a month ago. Any benefits, any adverse effects? Many tks

[Bocabarby in reply to Syncletica]

My husband sleeps better with a small amount mixed with honey!

[Hidden]

This was not the "same result" you reported 4 days earlier where you wrote "Yesterday morning I decided to start Thiamine and took 4 250 mg tablets at 6 am, Approx. 4hours after my parkinson's hit me like a ton of bricks : generalised muscular tension, giddiness, double vision, anxiety... and I had to lye down, until about 8 hours later these symptoms started to recede and returned to "normal" overnight. Anyone else had unwanted side effects from Vit. b1 ? and at what dose."

[aspergerian]

What brand? Perhaps your body is reacting to one of the excipients in the supplement, not necessarily to the B1. Become acquainted with SJS Syndrome and watch that your symptoms aren't indicating SJS, which is catastrophic.

mayoclinic.org/diseases-con...

[aspergerian13 in reply to aspergerian]

See also.

SJS Syndrome: meds, foods, herbs

healthunlocked.com/parkinso...

[Jmwg45]

You are right for you to stop and this is such a shame, and from what I can tell, very unusual. I agree with RoyProp that you make sure you are taking Thiamin HCL, but as with all these things we must do our own research and must always listen to our own bodies.

My own experience with Thiamin HCL has been very positive so I hope you find a way around this complication.

Anyone thinking of trying B1, this confirms you must proceed with some caution and work up to the full dose but my own research (please do your own) suggest side effects are rare and this reaction doesn't seem to fit b1 side effects. But one thing we know about PD - everyones is different.

I hope others are not put off but it is important that we have this feedback where people have experienced problems. Thank you for letting us know and good luck.

[stepan13]

ecub, what brand of b1 did you try?

Thank you - Stepan

[ecurb in reply to stepan13]

benerva hcl 125 mg

[aspergerian13 in reply to ecurb]

See:

Letter: September 13, 1941.

HYPERSENSITIVITY TO THIAMINE.

jamanetwork.com/journals/ja...

[Motherfather]

if you decied to try again try it with your doctor only by needle smaller doses.ill try it shortly sometime next week.

[ecurb in reply to Motherfather]

Thank you for advice, I think I can find 100 mg injectable here. Might try this week.

[Islandhappy]

I started with 100 mg thiamine. Taking it slow.