After taking 0.5 mg Rasagiline for the past 6 months with no noticeable adverse effects, recently I started having daily mild headaches and heart palpitations, which previously were only occasionally. I'll be seen my neurologist in a couple of weeks, but meanwhile gradually started reducing Rasagiline and seem to feel better in that regard. I am prone to having excess histamine and wonder if Rasagiline inhibits histamine degrading enzymes (DAO and HNMT) which I have genetic glitches with. Just wonder if anybody else had similar issues?
Going off Rasagiline: After taking 0.5 mg... - Cure Parkinson's
Going off Rasagiline
Although most of the research suggests that MAO-Bs do not interact with certain foods (containing tyramine) the way MAO-As do, perhaps you are having the response that some have reported. Do an internet search and examine the foods you eat. Fermented foods and aged cheeses are some of the culprits.
How do you gradually reduce from that? Isn't that the lowest dosage? I've been on since dx 1.5 yrs ago. That's all I take. I had major stomach pains. A horrible reaction. I thought it was bc of the tyramine too. I quit taking cold turkey for a couple weeks then tried again while watching food. I never had any problems again with it. And now I eat whatever I want. I think the bad reaction was from drinking too much coffee with it. I'm fine if I stick with 2 cups daily.
Also, taking sugar out of your diet will completely help your symptoms you've mentioned
Each time I started with a new drug (rasagiline, rotigotine and L dopa) I have had headache, nausea etc) and I noticed that it was due to big stress. My solution was to take 1/2 xanax to pass these difficult stages