Stiff arms and hands and restless leg for two days why?

[Bailey_Texas]

Cause different makers of med (Ropinirole). Just found out so can't type much. Always check maker on your meds.

Makers are

Dr. Reddy Good one for me Cost for 30 pills $180 us Pharmacy loses $45 to fill DR. Reddy insurance only pays $135

sandoz bad one for me Cost for 30 pills $5 us Makes $3 too fill

Wonder why DR. Reddy works better

[racerCP]

Bailey,

Hope you get better soon. Miss your posts and inspirational comments.

[bennett1]

Hiya from the UK. It's to do with the coating on the tablets. The better the coating the slower it breaks down and the longer the fix. Re your not being able to write much - have you tried going into the settings on your computer and slowing down the response times to suit you?good luck

[honeycombe3]

Hi Bailey,

Sorry you are having this problem. I encountered the Requip (Ropinirole) situation a few months ago. Having worked with my support team to overcome most 'freezing' episodes I was going through a bad patch mobility wise for no apparent reason. I had a Urinary Tract Infection which brought on a 4 day spell of being unable to move except for my head, fingers & toes. When I finished my course of antibiotics it took a long time to recover any degree of normality, especially mobility. At my next consultant clinic I was in a bad way & he asked me if I had recently had my Ropinirole levels checked because there was a problem with one brand which had led to problems in 8 of his patients. When tested there was no trace of Ropinirole. I returned to Requip & I am almost back to normal. I have taken this drug for 13 years - the only consistent med for PD.

[Don_oregon_duck in reply to honeycombe3]

The question I have is, how can we know about these differences BEFORE we start taking pills from a new supplier. Is there a lookup table somewhere so all of us won't have to repeat the same experience over and over?

Here's to a speedy recovery, Bailey.

[Bailey_Texas in reply to Don_oregon_duck]

That is the problem there is no difference they are the same med. I had the problem with c/l and some one here was taking the one i had problems with and could not take the one i liked. So depends on which one you start with.

Confusing huh

[johntPM]

I think the problem you are having is that there is less active ingredient in your generic. A generic does not need to be EXACTLY the same as the original.

"The FDA considers two products bioequivalent if the 90% CI of the relative mean Cmax, AUC(0–t) and AUC(0–∞) of the test (e.g. generic formulation) to reference (e.g. innovator brand formulation) should be within 80% to 125% in the fasting state."

en.wikipedia.org/wiki/Bioeq...

For most conditions this would not matter, but with PD the difference can have a noticeable effect.

John

[Bailey_Texas]

Thanks for the info.

I am back on DR. Reddy and doing a lot better. I got a new scrip for 2 pills a day and the insurance requires a pre authorisation so i had to buy 20 pills to get me through the process they cost me $162.