Grapefruit fruit & Sinemet: Does anyone... - Cure Parkinson's

Cure Parkinson's

25,550 members26,870 posts

Grapefruit fruit & Sinemet

RobertoOcana profile image
7 Replies

Does anyone knows, scientifically, if there is reaction, positive or negative, between grapefruit and Sinemet? Love the juice but .....?

Written by
RobertoOcana profile image
RobertoOcana
To view profiles and participate in discussions please or .
Read more about...
7 Replies

That is unfortunate , because you can not have it any more, ever.

The relationship between grapefruit and medications is very well scientifically understood and documented. The warnings clear. It interacts in several ways, the main two possible interactions being:

- a very quick and uncontrolled increase in the drugs strength / absorption to toxic levels

- a complete blockage of the medication absorption in the bowels that can last a very very long time after you take the grapefruit.

Try prune juice , a nice big glass every day, healthy in so many ways.

NO more grapefruit for you

( anything that you can not put in JELLO can not be good for you anyway)

park_bear profile image
park_bear

Here is list of grapefruit - drug interactions: cmaj.ca/content/suppl/2012/...

Whenever starting a new drug, always check interactions both using an interaction checker such as the one at drugs.com: drugs.com/drug_interactions... and by a general internet search on "new drug" "existing drug 1...n", for each existing drug, where grapefruit is included as one of them.

AFAIK grapefruit does not interact with my particular meds and I do have some from time to time.

Beckey profile image
Beckey

I don't know about sinemet, but I know you can't eat grapefruit or drink grapefruit juice while taking nilotinib, because it magnifies the effect to a dangerous level. I don't know if it has that same effect with other meds.

FMundo profile image
FMundo in reply to Beckey

Beckey, do you take Nilotinib for Parkinsons. Who prescribes it?

Tato profile image
Tato

Thanks all. Guess that's the end of grapefruit for me, why play Russian roulette? I just squeezed 4 gallons. As for the advice of GymBag are you aware of the amount of sugar in prune juice? When you get to certain age sugars are very bad.

JohnPepper profile image
JohnPepper

Hi Robertio. If you Google, Parkinson's, Mdication and grapefruit you will find that it is contraindicated.

RobertoOcana profile image
RobertoOcana

Thanks, have to dump 4 gallons of recently squeezed juice (have 4 tree full of fruits)

You may also like...

Reduction of Sinemet

Anyone have success in reducing their Parkinson medication, or at least reducing the amount of...

Sinemet and shakiness

Curious if anyone has ever experienced tremoring and more shakiness after you taken Sinemet? I take...

Grapefruit Juice dosing, another perspective

with my acupuncturist regarding the use of grapefruit juice. Two weeks ago I shared with him the...

Sinemet dose intervals

Is anybody here taking their Sinemet less than four hours between doses? I’m finding that lately...

Titrating down on Sinemet experience

originally prescribed 25/100 3 tablets per day (sinemet) 2 years ago. RH tremor was my only major...