Sinemet: Sinemet made my stiffness and... - Cure Parkinson's

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Sinemet

Beckey profile image
27 Replies

Sinemet made my stiffness and dystonia (that thing that makes you feel like you're going to push your foot out of the bottom of your shoe) worse. Shall this, too, pass? Or am I taking too much of a good thing?

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Beckey profile image
Beckey
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27 Replies
TheresaCurley profile image
TheresaCurley

It hasn't happened to me so far. I'm just curious, how long have you been on sinemet and what is your dosage?

Beckey profile image
Beckey in reply toTheresaCurley

25/100. A half a pill three times a day. It's been about three months.

Bailey_Texas profile image
Bailey_Texas

Give it a couple of weeks if you can. My side affects started getting better and finally for the most part went away.

Beckey profile image
Beckey in reply toBailey_Texas

Did they get worse before they got better?

Bailey_Texas profile image
Bailey_Texas in reply toBeckey

Any thing is possible. You are on such a small dose. I would ask to increase it. A larger dose might get you more close to normal.

Just a thought

Boyce3600 profile image
Boyce3600 in reply toBeckey

Without going back to previous posts of yours, the comment from parkbear causes me to ask these couple of questions:

Besides tremors, what were your symptomswhen you were diagnosed?

How long ago did you receive the diagnosis?

Beckey profile image
Beckey in reply toBoyce3600

My tremor started the first time back in 2006 and affected by right foot and hand. I saw a neurologist, he prescribed neurontin, and that took care of the problem.

Then, in early 2012, the tremor came back, but only in my hand/arm. It brings on a lot of pain -- the result of what the doctor called involuntary "bracing." That is just about the only consistent symptom I have, although I started having more difficulty walking before I started Rock Steady Boxing.

A second DaTscan showed increased abnormality, but on my right side. The doctor said with Parkinson's, it should be on the left if my tremor is on the right. But she still feels I show definite signs of PD, like if she raises my arm up over my head, my head shakes. And my arm with the tremor does swing normally.

Boyce3600 profile image
Boyce3600 in reply toBeckey

Thank you. This is interesting. Are you still taking the neurotin? Have not heard of that one, but still new to this.

Beckey profile image
Beckey in reply toBoyce3600

Naw, this time around neurontin was a dud.

park_bear profile image
park_bear

Sinemet equivalent (time release C/L 50/200 mg 3x/day) relieved my stiffness dramatically. A heavy dose of immediate release C/L, say 50/200, can cause me dystonia/dyskinesia, but only briefly. The amount you are taking is very small. That says to me your brain already has adequate dopamine to begin with and you do not have Parkinson's.

As you know, I have long thought that your tremors are an adverse reaction to the psych meds and this seems to confirm that.

Beckey profile image
Beckey in reply topark_bear

Man, I feel like I'm at sea. Without a sail!

park_bear profile image
park_bear in reply toBeckey

Did you ever get a second opinion? If not, I would recommend that.

park_bear profile image
park_bear in reply toBeckey

Another approach would be to ask your existing MD to order a DAT scan. I she agrees and you do, be sure to get a copy of the test report for yourself.

Kaykaykay123 profile image
Kaykaykay123

Since being on sinemet I too have had this with my foot! I thought it was a new symptom but maybe not

rhenry45 profile image
rhenry45 in reply toKaykaykay123

Tell your neurologist you want Botox injections in your affected foot and this will go away.

Johnfra profile image
Johnfra

Hang in there beckey it will get better👍

I take Sinemet and the lower part of my legs are red and sore. The doctor as giving me some cream to rub on them. Legs also feel very tired.

Johnfra profile image
Johnfra

How you feeling beckey?

Beckey profile image
Beckey in reply toJohnfra

It was a Rock Steady Boxing day, so better than usual, thanks!

Johnfra profile image
Johnfra in reply toBeckey

How you been beckey

Beckey profile image
Beckey in reply toJohnfra

Didn't go to RSB for about 10 days or so and boy was that a mistake. I was moving around like I was tipsy! After going Sunday and a workout today I feel better. I'm not going to let that happen again!

How YOU doing?

Johnfra profile image
Johnfra in reply toBeckey

Doing OK Becky going one day at a time glad you're feeling better you keep working hard and smiling it all pay off nice hearing from you Becky looks like a Lot of new promising drugs are coming out for us .👍

How you sleeping?

aloha24 profile image
aloha24 in reply toBeckey

My sister was diagnosed 3 years ago. She seems to throw up a lot in the mornings. Does anyone know if this could be from the Sinemet?

Beckey profile image
Beckey in reply toaloha24

When I started on sinemet, I felt pretty nauseous all the time and threw up so frequently I doubted any of the meds were making it to my brain. At first my neurologist told me to take an extra carbidopa (25 mg), but that didn't do the trick, so she prescribed something called Ondansetron. I take one every 8 hours. What a relief!

aloha24 profile image
aloha24 in reply toBeckey

Thanks Becky, yes she's taken that, otherwise known as Zofran but don't think she takes it on a regular basis. Will find out.

surfgirlhj profile image
surfgirlhj

Exercise,yoga and eletrolyte balance. Plus if time release it can effect u.

Different...i use kalapin to help atnight anti spasmatic. One thing i have learned is the drug never do the same thing each time . The overdose looks like an underdose...so caution

Hikoi profile image
Hikoi

Becky

I'm wondering about what you are calling dystonia. Is it painful because dystonia is, it's like having a cramp.

parkinsons.org.uk/sites/def...

For what it's worth I think your symptoms are from under medication but unless you increase your dose you won't know. When ever I take a dose of sinimet my symptoms get worse for a little while then settle. It's due to the changing levels. If I don't take enough to get to a therapeutic level I just have symptoms but no relief.

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