Boost Dopamine With Pine Pollen

youtube.com/watch?v=cqoH_Bq...(Not working as expected?)

[Madzy]

He mentioned some other things in this video like nutmeg, something with passionflower and munuca . As english is not my first language and he talks pretty fast I cannot make out which more things he mentioned . Can anyone tell me. And how fresh the powder has got to be?

[Joanne_Joyce in reply to Madzy]

I couldn't catch what he said about Turmeric and MAO inhibitors either. I've been adding turmeric in my diet and from what I thought he said, we shouldn't be using it. Does anyone understand this who can clarify this?

[Roseyuk]

Interesting.

Does anyone know how or where to purchase please.

Willing to try anything, as my husband is very hard to Medicate,

And his Parkinsons is fast taking over. His life.

[zawy]

He sells pine pollen. He doesn't have Parkinson's. He just happened to mention it in this video.

Honey, pollen, and propolis ("bee glue" resin from trees) appear to be MAO inhibitors in the test tube.

Especially propolis. The active ingredient in it appears to be APIGENIN, which is available as a supplement. It protects against a-syn aggregation, ROS, increases BDNF, is an MAO inhibitor, and increases dopamine uptake.

Luteolin and apigenin are the main active ingredients in Chamomile (tea) and artichoke which can be bought as extracts. Their molecular weights are less than 400 (270) so they might cross blood brain barrier, although luteolin was found to not be bioavailable in one study, although its metabolites might be the active ingredients. 200 mg for either is the dose needed to copy the work in mice, but that is a bit high.

luteolin and apigenin "enhancing monoamine uptake" "monoamine transporter activators"

ncbi.nlm.nih.gov/pubmed/198...

apigenin is an inhibitor of liver enzyme CYP2C9 so the list in the link below needs to be consulted if you're taking medication. It will amplify the effect of any drugs listed in the "substrate" column by not letting them be broken down. Most notably NSAIDs.

en.wikipedia.org/wiki/CYP2C9

"In conclusion, apigenin and luteolin protected the dopaminergic neurons probably by reducing oxidative damage, neuroinflammation and microglial activation along with enhanced neurotrophic potential. The above results propose both these flavonoids as promising molecules in the therapeutics of PD. "

ncbi.nlm.nih.gov/pubmed/250...

Bee products are MAO inhibitors, propolis is stronger.

ncbi.nlm.nih.gov/pubmed/241...

Apigenin main active ingredient in propolis, targets the preferred MAO-B (less chees effect) strongest

ncbi.nlm.nih.gov/pubmed/254...