Day 5 Zanubrutinib

[FreoSue]

Am a little concerned with one of the side effects increased bleeding. I have chronic venous insufficiency in my left leg and despite wearing my compression stocking it looks worse today, more bleeding? Not sure who to see about this or what to do?

[Newdawn Administrator]

Hi Sue,

You need to be ringing your haematology team and reporting this side effect. I’m also on Zanubrutinib and can empathise with this issue (my stomach and chest have extensive petechiae) but with an existing problem, I’d advise you ask to speak to someone at your hospital. I’m given a number for an urgent concerns, hope you have one too.

Best wishes,

Newdawn

[FreoSue in reply to Newdawn]

Thanks Newdawn was not given any hospital or urgent numbers to call - I can only inform my specialist at his office tomorrow

[Newdawn Administrator in reply to FreoSue]

I think that’s a wise precaution Sue. Hopefully it may just be an exaggerated response in your case given your existing weakness in the vessels.

Newdawn

[FreoSue in reply to Newdawn]

I was advised to not make any changes and keep taking my medication, making me feel like I was overreacting.

[Newdawn Administrator in reply to FreoSue]

Not very helpful of them Sue but it’s still important to report these side effects and never feel that you’re over-reacting by doing so. You only need to read the possible side effects of Zanubrutinib to know why that’s important.

Newdawn

[bayside64]

I developed a hematoma after my second dose of Zanubrutinib. They discontinued it. Eventually, I was given Venetoclax.