cataract surgery while on Zanubrutinib

[Bethsaida]

I am having cataract surgery on my right eye in about a month. I will discuss at my next oncology visit how long I have to stop Zanubrutinib, but I wanted to know if anyone had a slower healing process as a result of being on treatment? I also have Fuchs dystrophy, but my corneas are still of normal thickness so no treatment for that yet.

[rcusher]

I had cataract surgery on both my eyes in March ( 2 weeks apart ). I am currently in a trial and on Pirtobrutinib. My trial doctor saw no reason for me to go off the Pirto as she considered the surgery as one that usually doesn't involve any bleeding.

I don't know about Zanabrutinib so it's whatever your doctor decides.

On an added note my eyes are excellent, do not need to wear glasses anymore, just sunglasses outside because everything is so much brighter and clearer.

Good luck, Jack

[Bethsaida in reply to rcusher]

Thank you. Maybe I won’t have to stop the med. I’ll ask.

[rcusher in reply to Bethsaida]

FYI, I am 78 yrs.old

[dmmck]

I am on zanabrutinib and will be having cataract surgery soon. My doctor told me I should go off zanabrutinib three days before and five days after surgery.

[Bethsaida in reply to dmmck]

Since I have been on Zanubrutinib for over a year, my choice would be to stop for a few days as I still have significant side effects but I will do what I’m told by oncology staff.

[AussieNeil Partner Administrator]

The official Brukinsa/zanubrutinib website brukinsa.com/#isi states:

Before taking BRUKINSA, tell your healthcare provider about all of your medical conditions, including if you:

- have had recent surgery or plan to have surgery.

- Your healthcare provider may stop BRUKINSA for any planned medical, surgical, or dental procedure

Long term follow-up of other BTKi drugs, has not shown any loss in effectiveness for patients who have had short pauses (such as for surgery). I expect the same will be the case with zanubrutinib.

Neil

[Bethsaida in reply to AussieNeil]

Thank you. I have an appointment a week before my cataract surgery and will discuss with nurse practitioner.