Monoclonal components

[grazia50]

Dears,

I have a question.

I am in treatment for my CLL (13q, not mutated, with monoclonal component in gamma zone) with 2 cps of Ibrutinib.

Since the beginning my IgG, IgM, IgA are quite low, but I never got any treatment because I had no issues with that.

The result of the treatment with Ibrutinib is acceptable, from the hematological point of view, but after a while something changed: there was the presence of monoclonal IgM k , low concentration,

Recently a new change: ipogammaglobulinemie associated with profile oligoclonal low concentration IgG and IgM (k+lamda). My doctor says that those changes can be a side effect of CLL, with no specific concern. I am not fully convinced.

How do you think those changes should be evaluated? could be that 2 cps of Ibrutinib are not enough?

Thanks for your suggestions...

[Skyshark]

What is "2 cps" of Ibrutinib?

[grazia50 in reply to Skyshark]

Sorry, tablets

[LeoPa in reply to Skyshark]

I thought capsules.