acute pericarditis

[Roll0verRover1]

Just had the most horrendous chest pain, to the emergency room, overnight stay. Swift, great workup, no coronary disease, no pulmonary embolism, no Aortic dissection.

Pericardial effusion, CRP of 22, turns out I have Pericarditis. Not fun. No vigorous exercise for 3 months/ Colchicine, Naproxyn.

Interacts with Ibrutanib, so have stopped it. Really want to figure out how to take it safety with new meds.

Anyone out there have this experience. Any ideas?

[lankisterguy Volunteer]

Hi Roll0verRover1

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Here is a link to the 5 previous postings that mention it: healthunlocked.com/cllsuppo...

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I have no direct experience, and from the low number of past discussions, it seems fairly rare for us with CLL.

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I hope you can recover and get back to a normal life.

For guidance on taking the two drugs you should contact your medical team ASAP, there may be a way to do it, but this forum and any non expert medical sources are too risky to use.

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Len

[esn1967]

Good morning, RollOverRover1,

I cannot speak to pericarditis w/Cll, however, in 2019, 3 years prior to my CLL diagnosis , I ended up with pericarditis and a pericardial effusion after a long viral illness. My only symptom was having dyspnea for weeks- this led to many tests- and a CT scan picked up the pericardial effusion and I was sent to the ER for a work up. Luckily by this point the pericarditis was waning but I was stuck with the pericardial effusion for four years- it just began receding this year. (I've had an annual echocardiogram since then to monitor the effusion). No one told me not to exercise, but I was so fatigued for months that exercise was not really an option. My doctors were very concerned that I'd get sick again and that this would negatively impact the pericardial effusion/bring back the pericarditis so they directed me to wear a mask at work. This was just prior to covid and my HR Office was all freaked out, about me wearing a mask at work, and forcibly placed me on FMLA for wearing a mask. And I did not get sick again for four years until 13 days ago when I contracted covid for the first time.

I hope you are feeling better soon-

Emily

[SofiaDeo]

You haven't posted any info on your CLL so it's difficult to see if/to what extent your CLL is affecting anything. IDK why you feel a need stay on the ibrutinib, when the cardiac problem is life threatening.

The colchicine/NSAID combo is needed and there can be interactions with the ibrutinib, or potentiation of ibrutinib side effects. At this point, stabilizing the cardiac tissue is the goal. And if you docs thinks the ibrutinib contributed to the cardiac problem, you likely will not go back on it anyway. No need to rush, get the heart issues under control.

[hervec]

Bonjour

Automn 2019 I was under ibrutinib since march 2018 I had pericarditis. They tried 3 combinaisons.

Cotisone without colchicine (colchicine could interact with azithromicine) for 2 weeks result = ineffective

Aspirin 3000 for 2 weeks result = ineffective

Antalnox 550 x 2 (Naproxyn) 10 days result = ineffective

It ended with kineret for 6 month

I never stopped Ibrutinib

During this episod my C reactive protein was evolving around 300

Herve C