Combined Medication

[wolfe1963]

Hi Everyone first post as a new member. I am currently on one tablet of ibrutinib per day for 3 months. My 3 month ends on 27th of December. I then combine ibrutinib with Venetoclax for the remaining 15 months. Has anyone out there been on the same combination of tablets and could share their experience with me

[Newdawn Administrator]

I was on the Ibrutinib & Venetoclax combination and it successfully pushed my CLL into full remission (uMRD). Just make sure you keep very well hydrated on the Venetoclax ramp up. It’s a highly effective combination yielding excellent results in clinical trials.

Best wishes,

Newdawn

[wolfe1963 in reply to Newdawn]

Thanks for the reply will take on board what you said 🤞

[Snakejaw]

On a similar ride, been on zanubrutinib for three months, start Venetoclax on 12/21. So far so good, side effects negligible thus far.

[wolfe1963 in reply to Snakejaw]

Thanks for sharing. Good luck and hope everything goes well for you.

[Guinness4822]

Yes exactly the same. I've just started Venetoclax. No side effects hope the same for you.

[Smiley60]

Hi and welcome!I’m on a similar pathway to you of Ibrutinib started in September, followed by the addition of Venetoclax started beginning of December. So far so good, a few minor side effects, however the main effects have been positive, I’ve an increase in energy, feeling more with it and dramatic reduction in lymphocytes.

Best wishes

[Skyshark]

You should have 300mg/day allopurinol to reduce uric acid build up.

The total duration is 15 cycles, cycles are 4 weeks, total is 60 weeks. 3 cycles Ibrutinib, 1 cycle Ibrutinib + Venetoclax ramp up, 11 cycles Ibrutinib + Venetoclax.

[CoachVera55]

I want the Zanubrutinib & Venetoclax combo too but can only tolerate 1/2 dose of Zanubrutinib at the moment🤔