Paxlovid and Ibrutinib

[Ngtinfu]

I just tested positive for Covid. Can I continue to take Ibrutinib while I'm on Paxlovid?

Thanks.

[AussieNeil Partner Administrator]

Paxlovid increases the blood serum level of ibrutinib, so unless you stop or at least reduce your ibrutinib dose, you risk an increase in ibrutinib side effects/adverse events. Talk to your CLL specialist. There is little risk in stopping ibrutinib for 5 days. It's done for surgery.

Wishing you a quick recovery.

Neil

[LuzyCLL]

So sorry to hear that you have covid! I hope you recover soon. I will be thinking about you.

[RobertCLL]

I had covid over Christmas and received Paxlovid. I stopped my Ibrutinib for 7 days with no side effects from stopping.

[Rt2000]

The NIH has a whole list of drugs that should not be taken with Paxlovid. I had to stop Imbruvica and a statin I am taking for the week. Check:

covid19treatmentguidelines....

[croakerUK]

My team nurse told me to stop for 2 weeks. But by end of week two I was testing positive again,been negative for 6 days. Stopped Acalabrutinib for another 2 weeks and blood was normal when tested before I restarted taking Acalabrutinib again.

[naddude]

I take Calquence half dose 100 mg a day in the AM. How long would you stop before starting Pax

Pax