Here Is A Good Article About Covid Antibody Levels. Explains In Simple Terms Why We Vaccinated "CLL'ers" Have Covid Protection....

[DanBro1]

msn.com/en-us/health/medica...

[seelel]

I'm not sure that the article does what you say it does......'Explains In Simple Terms Why We Vaccinated "CLL'ers" Have Covid Protection....'

The article is written by a medical graduate writing for the ABC news. Someone who has probably simply read a few papers before going to press.

The premise is that with limited or decreased antibodies, the T-cells may provide the required protection from Covid. The author also uses the word 'probably'

The article is clear that science does not have a measure of immunity at this point in time. I quote: 'But scientists are still searching for a so-called "correlate of protection" -- a marker in the blood that would reliably indicate protection.'

So medical science is still on the back foot regarding levels of protection in healthy vaccinated people, let alone us immunocompromised mob.

[Indolent]

So, we are told not worry about the lack of antibodies because the T cells will do the job. But 44% of breakthrough infections were immunocompromised. To me, that indicates that the T cell response was not up to the task. What is missing are the statistics on how those immunocompromised breakthrough infections fared. Did they require hospitalization? What are the mortality numbers? Not knowing that, the only safe assumption continues to be that anyone who is immunocompromised and vaccinated is still at high risk.

[bkoffman CLL CURE Hero]

Low antibodies means you are probably not well protected and high antibodies means you may have some partial protection, but I would still act as if not vaccinated. The data are starting to support this. True that it's not proven, but it's true with most other viruses and vaccinations. We will need to easily measure neutralizing antibodies to get better info. I am sure that is coming. T cells aren't gonna save most of us with CLL.

[SeymourB]

DanBro1 -

I think all past antibody studies are quickly going to be out of date due to Omicron.

Not CLL specific, but early data from Denmark covering the first 785 cases of Omicron through 9 December, 2021, with indicate more breakthrough infections, even in boosted patients. This was at a time when Omicron was only 9.2% of all cases there:

eurosurveillance.org/conten...

Epidemiological characterisation of the first 785 SARS-CoV-2 Omicron variant cases in Denmark, December 2021

Data on mortality in that paper is scant, and should not be relied on. But 7 day averages for deaths in UK and Denmark still look pretty good, despite growing Omicron cases:

ourworldindata.org/covid-de...

Danish COVID-19 dashboard Progression in the number of hospitalised patients with confirmed COVID-19 shows that hospitalization, ICU, and ventilated cases are not as bad yet as last year:

sst.dk/en/english/corona-en...

So, it's really hard to say how well CLL patients who have had 2 primary doses plus a 3rd dose are prepared for the weeks to come. I urge caution.

=seymour=