THIRD SHOT BEING RECOMMENDED BY CDC FOR IMMUNO... - CLL Support

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THIRD SHOT BEING RECOMMENDED BY CDC FOR IMMUNOCOMPROMISED

wizzard166 profile image
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As a follow up to my post last week about getting a third shot, news stories caught my eye yesterday that I thought I'd pass on. As a precursor to some who missed my first post, I took it on my own to get a third shot without authorization. Now it appears that the government in the US is likely to start recommending the third shot to CLL patients and other immunocompromised. Here is the story in Cut and Paste fashion, for those who can't access the link from cnbc

CDC group weighs Covid booster shots for immunocompromised people at higher risk of breakthrough infections

KEY POINTS

A CDC advisory group is considering whether fully vaccinated Americans with weakened immune systems need a booster dose of the Covid vaccines.

Immunosuppressed people represent 44% of hospitalized Covid breakthrough cases even though they make up about 2.7% of the U.S. adult population, according to the agency.

They are also more likely to become seriously ill from Covid, the agency said, and are at a higher risk of transmitting the virus to family and friends

A CDC advisory group is considering whether fully vaccinated Americans with weakened immune systems need a booster dose of a Covid vaccine after data shows they are less likely to have antibodies to fight the disease and more likely to suffer from a so-called breakthrough infection.

Immunosuppressed populations represent 44% of hospitalized Covid breakthrough cases — an infection in a fully vaccinated individual, according to a slide presented Thursday at the agency’s Advisory Committee on Immunization Practices meeting. The population segment, which includes patients with cancer, HIV or those who have had organ transplants, represents only about 2.7% of the U.S. adult population, the presentation said.

The Centers for Disease Control and Prevention’s advisory committee is also meeting to discuss the safety profile of the Johnson & Johnson vaccine.

Immunocompromised people are more likely to become seriously ill from Covid and are at a higher risk of transmitting the virus to family and friends, the agency said.

Studies suggest that a third vaccine dose might help patients whose immune systems don’t respond as well to a first or second dose. Four small studies cited by the CDC showed that 16% to 80% of people with weakened immune systems didn’t have detectable antibodies to fight Covid after two shots.

Among immunosuppressed patients who had no detectable antibody response, 33% to 50% developed an antibody response after receiving an additional dose, according to the CDC.

“Emerging data suggest that an additional COVID-19 vaccine dose in immunocompromised people enhances antibody response and increases the proportion who respond,” according to one slide presented at the meeting.

The meeting comes as federal officials say booster doses of the vaccines for the general population are not needed at this time.

The advisory panel cannot recommend additional shots for anyone until the Food and Drug Administration grants full approval of the Covid vaccines or amends the emergency use authorizations.

Other countries, such as France, are already giving out third shots to people living with cancer or other immune impairments. The CDC group has previously said that more vulnerable Americans, such as elderly people or transplant recipients, may need an extra dose.

Some doctors have been pushing for the U.S. to allow immunosuppressed populations to get an extra dose, according to Dr. Dan Barouch, an immunologist at Harvard Medical School who helped develop the J&J vaccine.

“The hardest to vaccinate people are those who are immunosuppressed,” he said, adding early data shows a third shot may be safe and effective for those populations.

Dr. Camille Kotton, a member of the CDC’s advisory group, said Thursday that many immunosuppressed people are finding additional doses of the vaccines on their own.

“I am concerned about them doing this kind of in an unsupervised fashion, but as it is right now, due to regulatory issues we are not allowed to recommend additional doses so patients are really just doing what they think is best.”

— CNBC’s Rich Mendez and Robert Towey contributed to this article.

Enjoy

Carl

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wizzard166
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rafew profile image
rafew

After my first two doses of the moderna vaccine my CLL doctor ran a spike protein test which came back negative. But based on early responses from a study of immuno compromised transplant patients he wrote a letter to my primary requesting I receive a third shot. I haven’t yet retested, but by my reaction to the shot all indications are positive. I find myself privileged to have been able to get that third shot. (As a side note, I drive a bus for adults with disabilities and seniors with mobility issues)

Pin57 profile image
Pin57

Great update wizzard166 and I enjoyed reading the interior article within your article too:

“Americans are ‘mixing and matching’ Covid vaccines over concerns about the delta variant”

3rd shot approval is gonna happen for sure, shoot they planned for it long ago by stockpiling booster shots for the entire US!

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