Chinese exploration of nationals for 98% IGHV ... - CLL Support

CLL Support

22,720 members38,980 posts

Chinese exploration of nationals for 98% IGHV gene identity cutoff

cllady01 profile image
cllady01Former Volunteer
1 Reply

This is a 2020 article giving details of Chinese study to see if their patients should have the same IGHV gene identity cutoff to suggest Mutation as western patients.

The 98% gene identity and anything below that % suggests mutated.

ncbi.nlm.nih.gov/pmc/articl...

Written by
cllady01 profile image
cllady01
Former Volunteer
To view profiles and participate in discussions please or .
1 Reply
Smakwater profile image
Smakwater

cllady,

Very interesting read. Much more information than my shrinking bean can absorb in one setting though. I was pleased when reading the last two paragraphs and the conclusion, as it was summarized well enough that I had enough memory left to do the data dump.

I would recommend to those who have had more than three cups of coffee to go straight to the last two paragraphs, and then come back to read the rest after the caffeine wears off.

Thanks for the jump start!

JM

You may also like...

Resistance-Associated Mutations in CLL Patients Treated With Novel Agents

agents. In 80% of patients with ibrutinib failure, acquired mutations in BTK and PLCG2 genes were...

Potential Early Drivers of Disease in Treatment-Naive CLL Identified

factors and 29 gene mutations in patients with TN CLL, mutated ATM and unmutated IGHV were the...

Gene mutation and inflammatory GI tract disease

broad context. This article quite fascinating in possibly linking a frequent gene mutation in CLL...

Potential cure for CLL

Clarity trial took 50 patients, some in the final stages of the disease and mutations. They had a...

A new kid on the block? Nemtabrutinib

hopes for patients with relapsed blood cancer” dated 11/06/2023. The gist of the article is this....