My wife Gabriella started Ibrutinib in January with the regular dose of 420mg/day as a first line treatment.
She is 13q delation mutated and ignited treatment mostly because her neck made her disfigured.
After a couple of weeks of intense pain , her doctor agreed to lower the dose to 280mg/day and until a month ago , everything went fine .
WBC went from 200 to 8 ,lymphocytes down to 4 , neutrophils 42% ,hemoglobins 12.5,paletets 183 .
Heavy periods during the last 2 month plus recurring Lyme disease has again made her life miserable and her doctor reluctantly agreed to try 140mg/day .
I have seen the tendency of doctors who think one pill a day should be enough but I would like to know if any of you are on this regiment and how it is working.
Also is it ok to go back to 280mg/day if numbers increase?
Thank you and good health to all