My friend will be doing a stem cell treatment for her cll. She will be at the Mayo Clinic. She has 17P that has cloned. What is the success

[Dawn-Marie]

She has been through imbutran now on ventalox platelets are at 65 so the ventalox is failing. She has been on the medication for approximately 2 years. Had only been DX for 5 years. The started tx right after DX with target therapy. I am wanting to know the success of stem cell tx???

[AussieNeil Partner Administrator]

Hi Dawn-Marie,

Stem cell transplant success is age dependant, which is why it tends to be offered to younger patients with aggressive, refractory CLL. There have been continuing developments towards achieving higher success rates, so your friend's outcome will considerably depend on where she has it done and how well they are keeping up with new developments. We do have a few members that have gone through stem cell transplants, including Dr Brian Koffman, who blogged about his experiences. His didn't take, but Ibrutinib then CAR-T has worked well for him.

Neil

[Dawn-Marie in reply to AussieNeil]

Thank you for responding! She is 56 years old. Going to be doing it at the Mayo Clinic in Minnasota. I talk to her about the Car T therapy . I guess they are doing this because of the clones.

[AussieNeil Partner Administrator in reply to Dawn-Marie]

Good to hear your friend is having her bone marrow transplant done at an internationally recognised CLL centre of excellence!

[Dawn-Marie in reply to AussieNeil]

My friend came out of her bone marrow test with NO CLL in the bone marrow! Thankyou Jesus! So the stem cell implant will be taking place. 6-8 weeks🙏Works!

[RitaV]

Hi Dawn, finally got on here. My treatment is on hold again because I'm doing so good. They have concerns with my antibodies so I have to trust them as they've done good and brought me this far. Love you my dear-dear friend!

[Dawn-Marie in reply to RitaV]

Love you my friend! This is good site to keep our fears down! I am going to try and get to a conference in Omaha. It’s put on by UMC relate to new treatments for cll. Love you my girl🙏

[RitaV in reply to Dawn-Marie]

Love you too~ Did you go to the conference and what was the outcome?

[Dawn-Marie in reply to RitaV]

I can’t get off work to go😞

[Canuck901]

How old is she ? Interesting , so why did she stop Venetoclax

[Dawn-Marie]

She stop because of MDR negative. She back on venetoclax and the plan now is car-t therapy. She had to many antibodies for stem cell.