This was looking at heakthy people with flu, obviously the risk is far higher in immunocompromised patients... more reasons to get your flu vaccine.
In the study, Mitsuru Toda, MS, PhD, from the US Centers for Disease Control and Prevention (CDC) Mycotic Diseases Branch, along with her team, shared documented evidence that more than one-third of patients with invasive aspergillosis lacked documented immunosuppressive conditions.
“We would like clinicians to be aware that invasive aspergillosis can not only occur in immunocompromised patients but also in previously healthy patients with severe influenza,” Dr. Toda said. “We would like clinicians to think of fungal infections when patients do not get better with treatment, and we would like to them to look out for invasive aspergillosis in the coming flu season.”
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contagionlive.com/news/seve...
Further...
Invasive aspergillosis in patients admitted to the intensive care unit with severe influenza: A retrospective cohort study
Incidence of invasive pulmonary aspergillosis was as high as 32% (38 of 117 patients) for patients with influenza who were immunocompromised, whereas in the non-immunocompromised influenza case group, incidence was 14% (45 of 315 patients).
On the contrary, invasive pulmonary aspergillosis developed in only 16 (5%) of 315 patients.
In patients in the influenza cohort with invasive pulmonary aspergillosis, the 90-day mortality was 51% and 28% in the influenza cohort without invasive pulmonary aspergillosis (p=0·0001).
mdlinx.com/journal-summarie...
From the Lancet Study
Interpretation
Influenza was identified as an independent risk factor for invasive pulmonary aspergillosis and is associated with high mortality. Future studies should assess whether a faster diagnosis or antifungal prophylaxis could improve the outcome of influenza-associated aspergillosis.
Covid booster shot and flu shot more or less at same time safe for CLL patients?
