My husband has been on Imbruvica for 29 days and had appointment with Oncologist today. His WBC has gone from 28,000 to 90,000 today. His Oncologist was not too concerned about the rapid increase in WBC. He said it was not uncommon to have a rapid rise when starting Imbruvica. He wants to recheck lab next week. He said if it continued to rise he would have to give him some medication to bring the WBC down?He also ordered Ultram for the wrist and joint pain that has gotten pretty severe this past week.
Thanks for your thoughts.