Noob question

[Gildford]

I keep seeing the term “fish “. I am sure that doesn’t mean one who lives in the water!

Would someone enlighten me on this. One question of many.

Thanks in advance

Don

[Hidden]

FISH Panel is a blood test that determines the exact "flavor" or Leukemia a person has and specific chromosome errors. Personally I love the whole story of how it was created...google Dr. Mary Lou Pardue and ISH test.

FISH stands for Fluorescence In Situ Hybridization and is extremely advanced science.

Scott

[Gildford in reply to Hidden]

Thanks Scott. Possibly this “fish” is how they determined I have SLL rather than CLL. I will certainly peruse the paper you mentioned. See if. a machinist can sort it out. Good question for my hematologist.

Thanks Again

Don

[Hidden in reply to Gildford]

I just like the story of Dr. Mary Lou Pardue....she refused her first Ph.D (from some place like Harvard) and made them give her a Master's instead "because a house wife couldn't get a doctorate, only a Master's" (this back in the 1970's) but then of course she went off to some other place like MIT and got another Ph.D. She is a real genius and mostly invented the whole ISH test (of which now there are many many FISH being one).

Scott

[Gildford in reply to Hidden]

Many very intelligent people are dedicated to solving this problem.

Don

[AussieNeil Administrator in reply to Gildford]

Hi Don,

This pinned post explains the difference between CLL and SLL. As you'll read, they are considered the same disease: healthunlocked.com/cllsuppo...

More on the FISH test here:

healthunlocked.com/cllsuppo...

Neil

[Peggy4]

It’s a test that looks for genetic changes in cells. The test looks for specific genes that occur in CLL. At least I think that’s right!

Peggy

[Hidden in reply to Peggy4]

It mostly focuses on chromosomes that had data deleted, or in the case of Trisomy 12 I think added. It tells what chromosome(s) the DNA strand had data deleted from (11p, Trisomy 12, 13Q, 17p and a few other less known)

Having learned to program computers 36 years ago I have to wonder who controls the delete data from Scott's DNA strand button.

Scott

[Gildford in reply to Peggy4]

Thanks, I am just starting my vocabulary, have a lot to learn.

Don

[Hidden in reply to Gildford]

There is a lot to learn Don, regardless if you have the CLL or someone else. I been coming here since I was diagnosed a year ago and it is for sure the best place for support and learning.

From what I can see, you should feel free to ask anything.

Scott

[Gildford in reply to Hidden]

As I said earlier this site and the people on it bring a certain peace of mind in knowing more about my situation.

Don

[kay9hayes]

I so agree

[lankisterguy Volunteer]

Hi Gildford,

Since you mentioned that this question is one of many, here is an introduction/ overview of CLL and common terms- very easy to read and understand

bloodwise.org.uk/info-suppo...

and a more advanced explanation of blood components:

cancerandiblog.wordpress.co...

blood cancers:

cancerandiblog.wordpress.co...

cancerandiblog.wordpress.co...

cancerandiblog.wordpress.co...

Or something similar as a white board animation/spoken dialogue:

healthunlocked.com/cllsuppo...

If you want to learn even more in more depth, and you enjoy reading text online, this site has an more comprehensive learning course that can also bring you up to speed on the CLL specific discoveries learned over the last few years

cllsociety.org/2016/03/diag...

cllsociety.org/cll-101/

If you do better with explanatory videos Start here:

patientpower.info/chronic-l...

Patient Power is a for-profit patient education website offers instructive videos and more on many health topics including CLL.

Among those videos is my favorite "explainer" of lab tests & results - Dr. Susan LeClair

patientpower.info/series/as...

here is a list of links to other resources: cllsociety.org/cll-links/

Len

[kathymac52 in reply to lankisterguy]

When you go on the patient power website, which I did, how to access the videos? Is there a library of topics??

[lankisterguy Volunteer in reply to kathymac52]

Make certain you join or log in then you can start with this one:

patientpower.info/video/a-m...

then this: patientpower.info/about-cll/

and then scroll down to see the first 9 of 24 videos

Len

[kathymac52 in reply to lankisterguy]

Thanks, not quite sure where I find those but will explore the website.....

[SMS-not-cll]

I am sending this email to all of you knowledgeable people. I was diagnosed in 2014, but just recently found and joined this community. I am stage 0 , W n W, but I have so much to learn about all the genetics of CLL and about my particular CLL blood genetic. I so appreciate all of your answers that share information, share links to information, and share names of the great doctors working in the CLL field so advances in diagnose and treatments continue to improve.

So, a great big THANK YOU to all for sharing the info. I’ve become more determined to be the one in control of my life with CLL as my knowledge base increases.

Wishing you good days and good health,

SMS