I've been taking Ibrutinib for 16 months. The first 8 months I had no problems. Now 7 months ago I started having a rash on my legs, some on my chest and shoulders. I saw my dermatologist and tried several creams. Triamcinolone Acetonide gives some relief. Now it is the worst it has been. My MD took me off Ibrutinib for 10 days but it didn't make a difference in the rash. My legs are getting pretty well covered with it now and I don't know what else to do. Any suggestions?