I am Canadian being treated in London, Ontario. I was diagnosed with SLL in early 2015 with an enlarged spleen and lymph node (but not sure how long it was pre-existing). It became CLL in late 2015. My white blood count was at 16 in Oct. 2016 and now at 15 lately. I have all the CLL symptoms on a daily basis including swelling, pain in the neck and fever. My oncologist does not recommend a biopsy at this time. My concern: at what point should the biopsy be done?