As I've posted here before I was diagnosed in Dec of 2014. Lymph nodes the size of golf balls and that was every single one in my body. W and W until May if 2016 when nodes had grown by another 50%.
Began Imbruvica in July of 2016...within a week my lymph nodes were nearly back to normal size. I experienced almost no side effects other than the dry cracked finger tips and more recently weight gain.
As if my last blood work and oncologist visit this past Wednesday I'm happy to report by Red Blood count and Hemiglobin are " normal " ( not normal for a person with CLL but normal person normal) and my platelet count is 113 ( acceptable for a CLL person)
Too early to discuss reduced dosage much less remission but I'm a mighty happy dude right now.