Imbruvica & HgB

[tryandtry]

Does Imbruvica affect Hgb much? Mine has dropped to barely above 10 in 2 months of Imbruvica treatment (although I've also had colds & sinus infections). Does such a big drop (from 12-13)seem common? Any ideas if it might come back when I resume Imbruvica treatment (I've stopped temporarily to fight sinus infections)?

[ikahan]

Why did you stop Imbruvica ? did your doc. recommended it ? my husband had a bad sinus infection first month after starting imbruvica and he just added an antibiotic but did not stop ibrutinib

[MsLockYourPosts Passed Volunteer]

I would definitely discuss this with your doctor, as bleeding can be an issue with imbruvica. You don't want to find out that there is an internal bleed going on somewhere!

[Pennycam]

Sinus infections are not uncommon in cll, or when taking inbrutinib. I have had several courses of doxycycline over the past 18 months whilst taking Ibrutinib- my haemoglobin levels are within normal parameters. Does the doc think something else may be going on? Hope you get to the bottom of it soon - and you can recommence your therapy.

[SunnyCA]

My doctor told me Ibrutinib can lower Hmg. I've been on it 7 months and mine continues to slowly improve but is still on the low side in the 10 range. My platelates are now normal. Infections can be common - curious why you went off the drug?

[tryandtry]

For info, my CLL MD told me to stop taking Imbrutinib because she thought it might interfere with recovery of sinus infection. Only off for 1 week, now, & I see her again on Monday.